Evidence map›Paper›PMID 38374125›Full record

ArticleScientific reports2024

In vitro SELEX and application of an African swine fever virus (ASFV) p30 protein specific aptamer.

Changchun Hu, Shuo Li, Jie Zhou, Dan Wei, Xueying Liu, Zhu Chen, Hongquan Peng, Xun Liu, Yan Deng

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Changchun HuHunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Hunan, 412007, Zhuzhou, China.
Shuo LiHunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Hunan, 412007, Zhuzhou, China.
Jie ZhouHunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Hunan, 412007, Zhuzhou, China.
Dan WeiHunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Hunan, 412007, Zhuzhou, China.
Xueying LiuHunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Hunan, 412007, Zhuzhou, China.
Zhu ChenHunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Hunan, 412007, Zhuzhou, China.
Hongquan PengDepartment of Nephrology, Kiang Wu Hospital, Macau, SAR, China.
Xun LiuDepartment of Nephrology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yan DengHunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Hunan, 412007, Zhuzhou, China. hndengyan@126.com.
Hunan University of Technology · CNInstitute for the Future · USKiang Wu Hospital · CNSun Yat-sen University · CN

Funding

2022 Special Project for the Construction of Innovative Provinces to Fight the COVID-19 Outbreak 2022SK2115Natural Science Foundation of Hunan Province of China 2022JJ30230
6 · The paper itself

Abstract

The African swine fever virus (ASFV) has caused severe economic losses in the pig industry. To monitor ASFV spread, the p30 protein has been identified as an ideal infection marker due to its early and long-term expression during the ASFV infection period. Timely monitoring of ASFV p30 enables the detection of ASFV infection and assessment of disease progression. Aptamers are an outstanding substitute for antibodies to develop an efficient tool for ASFV p30 protein detection. In this study, a series of aptamer candidates were screened by in vitro magnetic bead-based systematic evolution of ligands by exponential enrichment (MB-SELEX). An aptamer (Atc-20) finally showed high specificity and affinity (K

Indexed as

African Swine FeverAfrican Swine Fever VirusBiosensing TechniquesAnimalsAntibodies, ViralAptamers, PeptideOligonucleotidesPhosphoproteinsSwineViral ProteinsAntibodies, ViralAptamers, PeptideOligonucleotidesP30 protein, African Swine Fever VirusPhosphoproteinsViral Proteins

Identifiers

PMID38374125
PMCPMC10876938
OpenAlexW4391926679

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.