Evidence map›Paper›PMID 38374123›Full record

ArticleBMC sports science, medicine & rehabilitation2024

Association between ACTN3 (R577X), ACE (I/D), BDKRB2 (-9/+9), and AGT (M268T) polymorphisms and performance phenotypes in Brazilian swimmers.

Severino Leão de Albuquerque-Neto, Marcos Antonio Pereira Dos Santos, Valmir Oliveira Silvino, Jose Juan Blanco Herrera, Thiago Santos Rosa, Glauber Castelo Branco Silva, Bruno Pena Couto, Cirley Pinheiro Ferreira, Alexandre Sérgio Silva, Sandro Soares de Almeida and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Severino Leão de Albuquerque-NetoUnião Educacional do Nordeste (UNINORDESTE), João Pessoa, Paraíba, Brazil.ORCID http://orcid.org/0000-0002-7304-0527
Marcos Antonio Pereira Dos SantosDepartment of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, Piauí, Brazil. marcosedfisio@gmail.com.ORCID http://orcid.org/0000-0002-0755-6138
Valmir Oliveira SilvinoDepartment of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, Piauí, Brazil.ORCID http://orcid.org/0000-0002-1992-5199
Jose Juan Blanco HerreraBrazilian Confederation of Aquatic Sports, Rio de Janeiro, Rio de Janeiro, Brazil.
Thiago Santos RosaDepartment of Physical Education, Catholic University of Brasília, Brasília, DF, Brazil.ORCID http://orcid.org/0000-0003-0418-0945
Glauber Castelo Branco SilvaDepartment of Physical Education, State University of Piauí, Barros Araújo Campus, Picos, Piauí, Brazil.ORCID http://orcid.org/0000-0001-6546-6707
Bruno Pena CoutoSchool of Health and Behavioural Sciences, The University of the Sunshine Coast, Sippy Downs, QLD, Australia.ORCID http://orcid.org/0000-0003-1011-6405
Cirley Pinheiro FerreiraDepartment of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, Piauí, Brazil.ORCID http://orcid.org/0000-0003-3632-7358
Alexandre Sérgio SilvaAssociated Postgraduate Program in Physical Education of the Federal University of Pernambuco, Federal University of Paraíba, João Pessoa, Brazil.ORCID http://orcid.org/0000-0003-3576-9023
Sandro Soares de AlmeidaHospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-4392-0953
Gislane Ferreira de MeloDepartment of Physical Education, Catholic University of Brasília, Brasília, DF, Brazil.ORCID http://orcid.org/0000-0003-3551-5963
Universidade Federal do Piauí · BRUniversidade Católica de Brasília · BRBrazilian Academy of Sciences · BRCentro Universitário de João Pessoa · BRHospital Israelita Albert Einstein · BRUniversidade Federal da Paraíba · BRUniversity of the Sunshine Coast · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe influence of genetic polymorphisms on athletic performance has been widely explored. This study investigated the interactions between the polymorphisms ACTN3 (R577X), ACE (I/D), BDKRB2 (-9/+9), and AGT (M/T) and their association with endurance and strength phenotypes in Brazilian swimmers.

methods123 athletes (aged 20-30 years) and 718 controls participated in the study. The athletes were divided into elite and sub-elite (N = 19 and 104, respectively) and strength and endurance experts (N = 98 and 25, respectively). Hardy-Weinberg equilibrium was observed in all groups.

resultsConsidering the ACE polymorphism, it was observed a higher frequency of the DD genotype than expected in the strength experts of the elite group, whereas the strength experts sub-elite athletes had a higher frequency of the ID genotype (χ

conclusionACE and ACTN3 allele frequencies should be considered with regard to performance influencing factors in Brazilian swimmers.

Indexed as

Aerobic performanceGenetic polymorphismsStrengthSwimming

Identifiers

PMID38374123
PMCPMC10877830
OpenAlexW4391944627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.