Evidence map›Paper›PMID 38373984›Full record

ArticleBMC oral health2024

The Association of Salivary Flow Rate and Sleep Quality among Head and Neck Cancer Survivors after Radiotherapy.

Yen-Wen Shen, Wen-Chen Wang, Nan-Chin Lin, Valendriyani Ningrum, Tzong-Ming Shieh, Yin-Hwa Shih

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Post-radiotherapy xerostomia and quality of life in head and neck cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Yen-Wen Shen *School of Dentistry, China Medical University, Taichung, 40402, Taiwan.
Wen-Chen Wang *Department of Oral Pathology, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan.
Nan-Chin LinDepartment of Oral and Maxillofacial Surgery, Show Chwan Memorial Hospital, Changhua, 500009, Taiwan.
Valendriyani NingrumSchool of Dentistry, Baiturrahmah University, By Pass Km 15 Aie Pacah, Padang, 25586, Indonesia.
Tzong-Ming ShiehSchool of Dentistry, China Medical University, Taichung, 40402, Taiwan. tmshieh@mail.cmu.edu.tw.
Yin-Hwa ShihDepartment of Healthcare Administration, Asia University, Taichung, 41354, Taiwan. evashih@gm.asia.edu.tw.
China Medical University · TWAsia University · TWChang Bing Show Chwan Memorial Hospital · TWKaohsiung Medical University · TWUniversitas Baiturrahmah · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHead and neck cancer survivors suffer from xerostomia and sleep disturbances after radiotherapy, both of which affect their quality of life. This study aimed to explore the role of salivary flow in the oral health and sleep quality of head and neck cancer survivors.

methodsWe recruited 120 head and neck cancer survivors who were experiencing symptoms of dry mouth or sleep disturbances post-radiotherapy from a dental clinic. We gathered their socio-demographic and clinical data, measured their salivary flow rate, and recorded their dry mouth score using the summated xerostomia inventory. Additionally, a dentist collected the DMFT (Decayed, Missing, and Filled Teeth) index. The Pittsburgh Sleep Quality Index was employed to assess their sleep quality.

resultsIn this study, xerostomia was observed in nearly 80% of the cancer survivors. The concurrent prevalence of sleep disturbance and xerostomia was at 55%. After five years post-radiotherapy, there was a significant improvement observed in both the quality of sleep (p = 0.03) and the stimulated salivary flow rate (p = 0.04). Additionally, these improvements were noted to have commenced from the third year onwards. A significant association was found between stimulated salivary flow and dry mouth scores with poor sleep quality (p <  0.05).

conclusionsWe recommend that dental professionals prioritize managing both dental and mental health issues equally for head and neck cancer survivors who have undergone radiotherapy within the past 3 years.

Indexed as

Head and Neck NeoplasmsXerostomiaHumansQuality of LifeSleep QualitySurvivorsDMFTHead and neck cancerPittsburgh sleep quality indexRadiotherapySalivary flow

Identifiers

PMID38373984
PMCPMC10875849
OpenAlexW4391930178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.