Evidence map›Paper›PMID 38373937›Full record

ArticleBMC geriatrics2024

Evaluation of a pharmacist-led intervention to reduce drug-related problems in patients included in a home healthcare program: study protocol for a pragmatic randomized clinical trial.

Clara Salom-Garrigues, Enric Aragonès, Montse Giralt, Cecília Campabadal Prats, Ferran Bejarano-Romero, Laura Canadell

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05820945 (Evaluation of a Pharmacist-Led Intervention to Reduce Drug-Related Problems in Patients Included in a Home Healthcare Program), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05820945 naunknown statusnot on this map

Evaluation of a Pharmacist-Led Intervention to Reduce Drug-Related Problems in Patients Included in a Home Healthcare Program: A Pragmatic Randomized Clinical Trial

TypeinterventionalSponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaRan2020 to 2024Enrolled432ConditionsPolypharmacy, Potentially Inappropriate MedicationsArmsPharmacist-led medication review
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Clara Salom-GarriguesPharmacy Unit, Catalan Health Institute, Joan XXIII University Hospital, Camp de Tarragona Primary Care Area, 4 Doctor Mallafrè Guasch St, 43005, Tarragona, Spain. csalom.tgn.ics@gencat.cat.
Enric AragonèsResearch Support Unit, Catalan Health Institute, Camp de Tarragona Primary Care Area, Tarragona, Spain.
Montse GiraltDepartment of Basic Medical Sciences, School of Medicine and Health Sciences, Rovira i Virgili University, Tarragona, Spain.
Cecília Campabadal PratsPharmacy Unit, Catalan Health Institute, Joan XXIII University Hospital, Camp de Tarragona Primary Care Area, 4 Doctor Mallafrè Guasch St, 43005, Tarragona, Spain.
Ferran Bejarano-RomeroPharmacy Unit, Catalan Health Institute, Joan XXIII University Hospital, Camp de Tarragona Primary Care Area, 4 Doctor Mallafrè Guasch St, 43005, Tarragona, Spain.
Laura CanadellPharmacy Unit, Catalan Health Institute, Joan XXIII University Hospital, Camp de Tarragona Primary Care Area, 4 Doctor Mallafrè Guasch St, 43005, Tarragona, Spain.
Hospital Universitari Joan XXIII de Tarragona · ESPrimary Health Care · QASpanish Society of Family and Community Medicine · ESUniversitat Rovira i Virgili · ES

Funding

Jordi Gol Primary Care Research Institute (IDIAPJGol), Barcelona, Spain 7Z21/011
6 · The paper itself

Abstract

backgroundATDOM is the Catalan home healthcare program at primary care level. Patients in the home care program are usually frail, elderly people with multiple comorbidities. They are often polymedicated, leading to a high risk of drug-related problems (DRPs). Our hypothesis is that the pharmacist-led individualized review of the pharmacotherapeutic plans of ATDOM patients will be effective in improving the quality of treatments by reducing DRPs in terms of indication, adequacy, effectiveness, and safety.

methodsAim: To compare the effectiveness of a standardized pharmaceutical intervention for the review and optimization of pharmacological treatments in ATDOM patients with usual management practice.

designPragmatic randomized clinical trial with a comparable control group, with prospective follow-up regarding the intervention on the adequacy of the pharmacological treatment of patients in the ATDOM program.

settingPrimary care teams in the Camp de Tarragona Primary Care Area, Tarragona, Spain.

participantsFour hundred and thirty-two ATDOM patients will be recruited, those who are over 65 years old and who are currently undergoing pharmacological treatment. MEASURES: Effectiveness of a six-month long intervention in reducing DRPs per patient and polypharmacy. Additionally, in the intervention group we will evaluate the implementation of the proposals for change or improvement made by the responsible physician. ANALYSIS: The outcomes will be analyzed on an intent-to-treat basis and the analysis units will be the individual patients. Logistic regression and linear regression models will be used to evaluate the effects of the intervention on dichotomous and continuous variables versus the control arm. ETHICS: The protocol was approved by the Research Ethics Committee of the Jordi Gol Primary Care Research Institute (IDIAPJGol), Barcelona, (19/141-P). DISCUSSION: If the results of the pharmaceutical intervention are favorable, widespread implementation of the program could be possible. It could be extended to all ATDOM patients or outpatients in general. Interdisciplinary teamwork could be strengthened as a result, which would improve the healthcare continuum.

trial registrationRetrospectively registered. CLINICALTRIALS: gov Identifier NCT05820945; Registered 21 March, 2023.

Indexed as

Home Care ServicesPharmacistsAgedDelivery of Health CareHumansPharmaceutical PreparationsPragmatic Clinical Trials as TopicProspective StudiesRandomized Controlled Trials as TopicPharmaceutical PreparationsAged patientsDomiciliary careMedication reviewPharmacist practice patternPrimary health care

Identifiers

PMID38373937
PMCPMC10875819
OpenAlexW4391932280

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.