ArticleBMC infectious diseases2024
The first case report: diagnosis and management of necrotizing fusobacterium lung abscess via BALF next-generation sequencing.
Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Severe Necrotizing Community-Acquired Pneumonia and Bilateral Empyema in an Immunocompetent Patient due toCase reports in pulmonology · 2026Article
- Pneumonia with parapneumonic effusion due toWorld journal of emergency medicine · 2025Article
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7 authors at 1 institution in 1 country.
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Abstract
backgroundFusobacterium necrophorum (F. necrophorum)-induced necrotizing pneumonia is a rare but severe pulmonary infection. Insufficient microbiological detection methods can lead to diagnostic difficulties.
methodsWe report a case of F. necrophorum lung abscess diagnosed by next-generation sequencing (NGS) of bronchoalveolar lavage fluid (BALF).
resultsBALF-NGS detected F. necrophorum, guiding subsequent targeted antibiotic therapy. With active drainage and metronidazole treatment, the patient's condition was effectively treated.
conclusionBALF-NGS is a valuable tool for the rapid diagnosis of infections caused by difficult-to-culture bacteria. It played a decisive role in the early identification of F. necrophorum, enabling timely and targeted antibiotic intervention. Early diagnosis and appropriate treatment are crucial for the management of F. necrophorum pneumonia.
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