Evidence map›Paper›PMID 38373836›Full record

ArticleYonsei medical journal2024

Computed Tomography Radiomics for Preoperative Prediction of Spread Through Air Spaces in the Early Stage of Surgically Resected Lung Adenocarcinomas.

Young Joo Suh, Kyunghwa Han, Yonghan Kwon, Hwiyoung Kim, Suji Lee, Sung Ho Hwang, Myung Hyun Kim, Hyun Joo Shin, Chang Young Lee, Hyo Sup Shim

Abstract read
In one paragraph

Article in Yonsei medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Young Joo SuhDepartment of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. rongzu@yuhs.ac.ORCID https://orcid.org/0000-0002-2078-5832
Kyunghwa HanDepartment of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5687-7237
Yonghan KwonDepartment of Biostatistics and Computing, Yonsei University Graduate School, Seoul, Korea.ORCID https://orcid.org/0000-0001-7951-1142
Hwiyoung KimDepartment of Biomedical System Informatics, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7778-8973
Suji LeeDepartment of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8770-622X
Sung Ho HwangDepartment of Radiology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-1850-0751
Myung Hyun KimDepartment of Radiology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.ORCID https://orcid.org/0000-0002-5139-0155
Hyun Joo ShinDepartment of Radiology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.ORCID https://orcid.org/0000-0002-7462-2609
Chang Young LeeThoracic and Cardiovascular Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2404-9357
Hyo Sup ShimDepartment of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5718-3624

Funding

Yonsei University College of Medicine 6-2020-0209
6 · The paper itself

Abstract

purposeTo assess the added value of radiomics models from preoperative chest CT in predicting the presence of spread through air spaces (STAS) in the early stage of surgically resected lung adenocarcinomas using multiple validation datasets. MATERIALS AND

methodsThis retrospective study included 550 early-stage surgically resected lung adenocarcinomas in 521 patients, classified into training, test, internal validation, and temporal validation sets (n=211, 90, 91, and 158, respectively). Radiomics features were extracted from the segmented tumors on preoperative chest CT, and a radiomics score (Rad-score) was calculated to predict the presence of STAS. Diagnostic performance of the conventional model and the combined model, based on a combination of conventional and radiomics features, for the diagnosis of the presence of STAS were compared using the area under the curve (AUC) of the receiver operating characteristic curve.

resultsRad-score was significantly higher in the STAS-positive group compared to the STAS-negative group in the training, test, internal, and temporal validation sets. The performance of the combined model was significantly higher than that of the conventional model in the training set {AUC: 0.784 [95% confidence interval (CI): 0.722-0.846] vs. AUC: 0.815 (95% CI: 0.759-0.872),

conclusionA quantitative CT radiomics model can assist in the non-invasive prediction of the presence of STAS in the early stage of lung adenocarcinomas.

Indexed as

AdenocarcinomaAdenocarcinoma of LungLung NeoplasmsHumansRadiomicsRetrospective StudiesTomography, X-Ray ComputedLung adenocarcinomamachine learningpathologyradiogenomics (imaging)

Identifiers

PMID38373836
PMCPMC10896671

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.