Evidence map›Paper›PMID 38373648›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2024

A case-control study of risk factors for incident hepatitis B virus infection in South African blood donors.

Ute Jentsch, Marion Vermeulen, Karin van den Berg, Ronél Swanevelder, Darryl Creel, Genevieve Jacobs, Jennifer Jay Hemingway-Foday, Cynthia Nyoni, Edward L Murphy, Brian Custer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ute JentschThe South African National Blood Service, Johannesburg, South Africa. Electronic address: Ute.Jentsch@sanbs.org.za.
Marion VermeulenThe South African National Blood Service, Johannesburg, South Africa; University of the Free State, Bloemfontein, South Africa.
Karin van den BergThe South African National Blood Service, Johannesburg, South Africa; University of the Free State, Bloemfontein, South Africa.
Ronél SwanevelderThe South African National Blood Service, Johannesburg, South Africa.
Darryl CreelRTI International, Rockville, USA.
Genevieve JacobsThe South African National Blood Service, Johannesburg, South Africa.
Jennifer Jay Hemingway-FodayRTI International, Rockville, USA.
Cynthia NyoniThe South African National Blood Service, Johannesburg, South Africa.
Edward L MurphyUniversity of California San Francisco, San Francisco, USA; Vitalant Research Institute, San Francisco, USA.
Brian CusterVitalant Research Institute, San Francisco, USA; University of California San Francisco, San Francisco, USA.
South African National Blood Service · ZARTI International · USUniversity of California, San Francisco · USUniversity of the Free State · ZA

Funding

Research training in HIV-related transfusion medicine and hematology in South AfricaD43TW010345 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI UTE JENTSCH, EDWARD L MURPHY · 2017 to 2026
$3.0M
FIC NIH HHS D43 TW010345NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009IWHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100002C
6 · The paper itself

Abstract

objectivesHepatitis B virus (HBV) infection remains a global health problem. Risk factors for HBV infection are usually assessed in prevalent rather than incident infections. To identify demographic and behavioral risks associated with incident HBV among South African blood donors.

methodsA case-control study was performed between November 2014 and January 2018. Cases were blood donors testing positive for HBV DNA with or without hepatitis B surface antigen but negative for antibody to hepatitis B core antigen. Participants completed an audio computer-assisted structured interview on exposures during the previous 6 months. Sex-specific multivariable logistic regression yielded independent associations between risks and HBV infection.

results56 females and 37 males with incident HBV were compared to 438 female and 439 male controls, respectively. For females, risk factors were accepting money or goods for sex, using agents to prepare one's anus prior to anal sex, penetrating injury, non-Black race, and lower educational status. Men reporting homosexual or bisexual orientation or sex with other men, previous injury, referral for HBV testing, or lack of medical insurance were at increased risk. For both sexes, having more than two male sexual partners increased risk.

conclusionsSexual behaviors predominated over parenteral exposures as risks for incident HBV in both female and male blood donors.

Indexed as

Hepatitis BHepatitis B virusBlood DonorsCase-Control StudiesFemaleHepatitis B AntibodiesHepatitis B Core AntigensHepatitis B Surface AntigensHumansMaleRisk FactorsSouth AfricaHepatitis B AntibodiesHepatitis B Core AntigensHepatitis B Surface AntigensBlood donorsHepatitis B virusRisk factorsTransfusion

Identifiers

PMID38373648
PMCPMC11034725
OpenAlexW4391900173

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.