Evidence map›Paper›PMID 38373478›Full record

ArticleNeurochemistry international2024

The expression system influences stability, maturation efficiency, and oligomeric properties of the potassium-chloride co-transporter KCC2.

Morgan Kok, Karen Hartnett-Scott, Cassandra L Happe, Matthew L MacDonald, Elias Aizenman, Jeffrey L Brodsky

Open access · greenAbstract read
In one paragraph

Article in Neurochemistry international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. A novel pathogenicFrontiers in molecular neuroscience · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Morgan KokDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
Karen Hartnett-ScottDepartment of Neurobiology and the Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Cassandra L HappeDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Matthew L MacDonaldDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Elias AizenmanDepartment of Neurobiology and the Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jeffrey L BrodskyDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: jbrodsky@pitt.edu.
University of Pittsburgh · US

Funding

Liberation of Intracellular Zinc and Neuronal Cell DeathR01NS043277 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AIZENMAN, ELIAS · 2002 to 2022
$8.2M
Modulating Hsp70-dependent proteostasis in Alzheimer's DiseaseR35GM131732 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JEFFREY L. BRODSKY · 2019 to 2026
$3.4M
Synaptic Protein Networks, Genetic Risk, and Spine Loss in SchizophreniaR01MH118497 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MACDONALD, MATTHEW L · 2019 to 2023
$2.5M
Interinstitutional Program in Cell and Molecular Biology: A Graduate Training Path to Promote Traditional and Non-Traditional Professional OutcomesT32GM133353 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BRODSKY, JEFFREY L., MURRAY, SANDRA ANN · 2020 to 2024
$1.5M
Regulation of excitotoxicity by ZnT1R21NS117702 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AIZENMAN, ELIAS · 2020 to 2020
$412k
Liberation of Intracellular Zinc and Neuronal Cell DeathR56NS043277 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AIZENMAN, ELIAS · 2007 to 2007
$371k
NIGMS NIH HHS R35 GM131732NIGMS NIH HHS T32 GM133353NIMH NIH HHS R01 MH118497NINDS NIH HHS R01 NS043277NINDS NIH HHS R21 NS117702NINDS NIH HHS R56 NS043277
6 · The paper itself

Abstract

The neuron-specific K

Indexed as

K Cl- CotransportersAnimalsEndoplasmic Reticulum-Associated DegradationHEK293 CellsHumansPotassium ChlorideRatsSaccharomyces cerevisiaeSymportersK Cl- CotransportersPotassium ChlorideSLC12A5 protein, humanSymporters

Identifiers

PMID38373478
PMCPMC10923169
OpenAlexW4391896447

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.