ArticleJournal of the American Chemical Society2024
Measuring Protein-Ligand Binding by Hyperpolarized Ultrafast NMR.
Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Rapid Fragment Screening byAngewandte Chemie (International ed. in English) · 2026Article
- Physics-informed deep learning enables fast ultrahigh-resolution nuclear magnetic resonance spectroscopy.Communications chemistry · 2026Article
- Chemically induced deceleration of nuclear spin relaxation (CIDER) preserves hyperpolarization.Science advances · 2025Article
- One Tracer, Dual Platforms: Unlocking Versatility of Fluorescent Probes in TR-FRET and NanoBRET Target Engagement Assays.ACS medicinal chemistry letters · 2025Article
- Unconventional Parahydrogen-Induced Hyperpolarization Effects in Chemistry and Catalysis: From Photoreactions to Enzymes.ACS catalysis · 2025Review
- Parahydrogen Polarization in Reverse Micelles and Application to Sensing of Protein-Ligand Binding.Journal of the American Chemical Society · 2024Article
- Ultrafast Nuclear Magnetic Resonance as a Tool to Detect Rapid Chemical Change in Solution.ACS physical chemistry Au · 2024Review
- Cross-Polarization of Insensitive Nuclei from Water Protons for Detection of Protein-Ligand Binding.Journal of the American Chemical Society · 2024Article
- Hyperpolarization of Long-Lived States of Protons in Aliphatic Chains by Bullet Dynamic Nuclear Polarization, Revealed on the Fly by Spin-Lock-Induced Crossing.The journal of physical chemistry letters · 2024Article
- Rapid Protein-Ligand Affinity Determination by Photoinduced Hyperpolarized NMR.Journal of the American Chemical Society · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Protein-ligand interactions can be detected by observing changes in the transverse relaxation rates of the ligand upon binding. The ultrafast NMR technique, which correlates the chemical shift with the transverse relaxation rate, allows for the simultaneous acquisition of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.