Evidence map›Paper›PMID 38372801›Full record

ArticleCurrent microbiology2024

Green-Synthesized Silver Nanoparticles in the Prevention of Multidrug-Resistant Proteus mirabilis Infection and Incrustation of Urinary Catheters BioAgNPs Against P. mirabilis Infection.

Gustavo Issamu Asai Saikawa, Gustavo Henrique Migliorini Guidone, Sandriele Aparecida Noriler, Guilherme Fonseca Reis, Admilton Gonçalves de Oliveira, Gerson Nakazato, Sergio Paulo Dejato Rocha

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Species-Specific Stress Responses to Selenium Nanoparticles inNanomaterials (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gustavo Issamu Asai SaikawaLaboratory of Bacteriology, Department of Microbiology, Center of Biological Sciences, State University of Londrina, Rodovia Celso Garcia Cid PO-BOX 6001, Londrina, 86051-980, Brazil.
Gustavo Henrique Migliorini GuidoneLaboratory of Bacteriology, Department of Microbiology, Center of Biological Sciences, State University of Londrina, Rodovia Celso Garcia Cid PO-BOX 6001, Londrina, 86051-980, Brazil.
Sandriele Aparecida NorilerLaboratory of Microbial Biotechnology, Department of Microbiology, Center of Biological Sciences, State University of Londrina, Londrina, Brazil.
Guilherme Fonseca ReisLaboratory of Microbial Biotechnology, Department of Microbiology, Center of Biological Sciences, State University of Londrina, Londrina, Brazil.
Admilton Gonçalves de OliveiraLaboratory of Microbial Biotechnology, Department of Microbiology, Center of Biological Sciences, State University of Londrina, Londrina, Brazil.
Gerson NakazatoLaboratory of Basic and Applied Bacteriology, Department of Microbiology, Center of Biological Sciences, State University of Londrina, Londrina, Brazil.
Sergio Paulo Dejato RochaLaboratory of Bacteriology, Department of Microbiology, Center of Biological Sciences, State University of Londrina, Rodovia Celso Garcia Cid PO-BOX 6001, Londrina, 86051-980, Brazil. rochaspd@uel.br.ORCID http://orcid.org/0000-0001-8510-536X
Universidade Estadual de Londrina · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001
6 · The paper itself

Abstract

This study aimed to assess the activity of AgNPs biosynthesized by Fusarium oxysporum (bio-AgNPs) against multidrug-resistant uropathogenic Proteus mirabilis, and to assess the antibacterial activity of catheters coated with bio-AgNPs. Broth microdilution and time-kill kinetics assays were used to determine the antibacterial activity of bio-AgNPs. Catheters were coated with two (2C) and three (3C) bio-AgNPs layers using polydopamine as crosslinker. Catheters were challenged with urine inoculated with P. mirabilis to assess the anti-incrustation activity. MIC was found to be 62.5 µmol l-1, causing total loss of viability after 4 h and bio-AgNPs inhibited biofilm formation by 76.4%. Catheters 2C and 3C avoided incrustation for 13 and 20 days, respectively, and reduced biofilm formation by more than 98%, while the pristine catheter was encrusted on the first day. These results provide evidence for the use of bio-AgNPs as a potential alternative to combat of multidrug-resistant P. mirabilis infections.

Indexed as

Metal NanoparticlesMirabilisAnti-Bacterial AgentsProteus mirabilisSilverUrinary CathetersAnti-Bacterial AgentsSilver

Identifiers

PMID38372801
OpenAlexW4391928457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.