Observational studyLa Tunisie medicale2023
Prediction of intensive care unit mortality: Interest of serum lactates.
Observational study in La Tunisie medicale, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Combined lactate, base excess, and MEWS score as predictors of ICU transfer from the emergency department: a retrospective cohort study.Frontiers in medicine · 2026Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMany prognostic indices have been developed to assess clinical status and predict the probability of death in the intensive care unit (ICU) but none have perfect sensitivity or specificity.
aimTo evaluate the prognostic value of admission lactate in patients admitted to ICU.
methodsA cohort, observational, prospective study was carried out in the intensive care unit (ICU) of Mongi Slim Hospital, la Marsa, over 12 months period. Arterial blood lactate (ABL) was measured in ICU admission (H0), then 6 hours (H6), 12 hours (H12), 24 hours (H24) and 48hours (H48) after admission. Prognostic scores were calculated 24 hours after the admission. We also recorded biological data, hemodynamic parameters, and the evolution during the stay in intensive care. Primary endpoint was ICU mortality.
resultsWe included 135 patients. The average age was 47.22 ± 16.88 years with a sex-ratio of 1.75. ICU mortality was 48%. The mean ABL at admission was 3.05 ± 2.63 mmol/l, higher in the dead group with a statistically significant difference. Prognostic value of lactate at admission was less powerful than severity indices in this study but remains excellent with an AUC >0, 7 defining « cut-off » values with a good sensitivity and specificity. In multivariate analysis, initial lactate > 2 mmol/l was found to be an independent predictive factor of ICU mortality with an Odd Ratio [IC 95%] =1.16 [1.07 - 3.6]; p=0.04.
conclusionsMonitoring lactatemia in ICU could allow better identification of patients at high risk of death and the reassessment of therapeutic efficacy.
Indexed as
Identifiers
38372556PMC11217983W4394764952What OpenQuestion holds
Registered trials
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