Evidence map›Paper›PMID 38372553›Full record

Trial reportLa Tunisie medicale2023

Postoperative Analgesia in Breast Cancer Surgery: Efficiency and Safety of Ultrasound Guided Erector Spinae Plane Block, a randomized controlled double blinded trial.

Maryem Ben Amor, Sofiene Ben Marzouk, Salma Souihli, Bochra Fouzai, Feryel Ben Amor, Hayen Magherbi

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in La Tunisie medicale, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maryem Ben AmorDepartment of Anesthesiology and Obstetric Intensive Care, Tunis Maternity and Neonatology Center, Tunis, Tunisia. Faculty of Medicine, University Tunis El Manar, Tunis, Tunisia.
Sofiene Ben MarzoukDepartment of Anesthesiology and Obstetric Intensive Care, Tunis Maternity and Neonatology Center, Tunis, Tunisia. Faculty of Medicine, University Tunis El Manar, Tunis, Tunisia.
Salma SouihliDepartment of Anesthesiology and Obstetric Intensive Care, Tunis Maternity and Neonatology Center, Tunis, Tunisia. Faculty of Medicine, University Tunis El Manar, Tunis, Tunisia.
Bochra FouzaiDepartment of Anesthesiology and Obstetric Intensive Care, Tunis Maternity and Neonatology Center, Tunis, Tunisia. Faculty of Medicine, University Tunis El Manar, Tunis, Tunisia.
Feryel Ben AmorDepartment of Anesthesiology and Obstetric Intensive Care, Tunis Maternity and Neonatology Center, Tunis, Tunisia. Faculty of Medicine, University Tunis El Manar, Tunis, Tunisia.
Hayen MagherbiDepartment of Anesthesiology and Obstetric Intensive Care, Tunis Maternity and Neonatology Center, Tunis, Tunisia. Faculty of Medicine, University Tunis El Manar, Tunis, Tunisia.
Tunis El Manar University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBreast cancer surgeries are the mainstay and usually the first step of treatment.

aimTo assess the efficiency and safety of ultrasound guided Erector Spinae Plane Block (ESPB) for the management of postoperative pain in patients undergoing elective breast cancer surgery.

methodsBetween December 2018 and June 2019, a prospective, controlled, randomized, double-blinded study was conducted at the maternity and neonatology center of Tunis. We included fifty ASA I-II female patients who were scheduled for elective breast cancer surgery. They were randomly divided into two groups: Group R (n=25) with Ropivacaine, while Group P (n=25) received a placebo. The study recorded PCA morphine consumption and patient demand for PCA. The primary outcome was to compare the visual analogue scale (VAS) pain scores at various points throughout the 24 hours postoperatively (1st, 2nd, 4th, 8th, 12th, 16th, 20th, 24th) between the two groups.

resultsExcept for the first hour and 16th hour post-surgery, the mean VAS pain scores were significantly lower in Group R compared to Group P. The 24-hour morphine consumption was significantly lower in Group R (5.5±0.9 mg) compared to Group P (16.6±2.8 mg); p<0.001. Per-operative fentanyl consumption was also significantly lower in Group R (9.1±4.2 mcg; Group P: 50±9.1 mcg; p< 0.001). Moreover, the mean total morphine demand was significantly lower in Group R.

conclusionESPB with Ropivacaine is effective and safe for pain management after breast cancer surgery with a consequent morphine sparing and less use of systemic analgesia.

Indexed as

AnalgesiaBreast NeoplasmsNerve BlockDouble-Blind MethodFemaleHumansMorphine DerivativesPostoperative PainPregnancyProspective StudiesRopivacaineUltrasonography, InterventionalMorphine DerivativesRopivacaine

Identifiers

PMID38372553
PMCPMC11217957
OpenAlexW4394759229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.