Evidence map›Paper›PMID 38372177›Full record

ArticleCirculation. Genomic and precision medicine2024

Sex Differences in the Association of Multiethnic Genome-Wide Blood Pressure Polygenic Risk Score With Population-Level Systolic Blood Pressure Trajectories.

Naman S Shetty, Akhil Pampana, Nirav Patel, Krishin Yerabolu, Gnyata Patel, Marguerite R Irvin, Pradeep Natarajan, Henry J Lin, Xiuqing Guo, Stephen S Rich and 4 more

Registry-linked trialAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Genomic and precision medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06962488 (Clinical Implementation of Blood Pressure Polygenic Risk Score), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06962488 narecruitingnot on this mapstarted 2025, after this paper: background citation

Clinical Implementation of Blood Pressure Polygenic Risk Score

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2025 to 2030Enrolled300ConditionsHypertension, Atherosclerotic Cardiovascular DiseaseArmsRegular Care, SBP PRS Dissemination
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Differences of plaque burden measures on CCTA in younger men and women.American journal of preventive cardiology · 2026
    Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Naman S ShettyDivision of Cardiovascular Disease (N.S.S., A.P., N.P., K.Y., G.A., P.A.), University of Alabama at Birmingham.ORCID 0000-0003-3600-126X
Akhil PampanaDivision of Cardiovascular Disease (N.S.S., A.P., N.P., K.Y., G.A., P.A.), University of Alabama at Birmingham.ORCID 0000-0002-4167-0540
Nirav PatelDivision of Cardiovascular Disease (N.S.S., A.P., N.P., K.Y., G.A., P.A.), University of Alabama at Birmingham.
Krishin YeraboluDivision of Cardiovascular Disease (N.S.S., A.P., N.P., K.Y., G.A., P.A.), University of Alabama at Birmingham.ORCID 0009-0006-5678-7385
Gnyata PatelDepartment of Medicine (G.P.), University of Alabama at Birmingham.ORCID 0000-0002-6287-2651
Marguerite R IrvinDepartment of Epidemiology, School of Public Health (M.R.I.), University of Alabama at Birmingham.
Pradeep NatarajanCardiology Division, Department of Medicine, Massachusetts General Hospital (P.N.).ORCID 0000-0001-8402-7435
Henry J LinThe Institute for Translational Genomics and Population Sciences (H.J.L., X.G., J.I.R.), Harbor-UCLA Medical Center, Torrance, CA.ORCID 0000-0001-6771-0486
Xiuqing GuoThe Institute for Translational Genomics and Population Sciences (H.J.L., X.G., J.I.R.), Harbor-UCLA Medical Center, Torrance, CA.ORCID 0000-0002-5264-5068
Stephen S RichCenter for Public Health, University of Virginia, Charlottesville (S.S.R.).ORCID 0000-0003-3872-7793
Jerome I RotterThe Institute for Translational Genomics and Population Sciences (H.J.L., X.G., J.I.R.), Harbor-UCLA Medical Center, Torrance, CA.ORCID 0000-0001-7191-1723
Peng LiSchool of Nursing (P.L.), University of Alabama at Birmingham.ORCID 0000-0002-9026-9999
Garima AroraDivision of Cardiovascular Disease (N.S.S., A.P., N.P., K.Y., G.A., P.A.), University of Alabama at Birmingham.
Pankaj AroraDivision of Cardiovascular Disease (N.S.S., A.P., N.P., K.Y., G.A., P.A.), University of Alabama at Birmingham.ORCID 0000-0003-2420-3550

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrea L Hevener · 2003 to 2026
$40.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Task Area A Core Study Operations.Task Area A shall encompass annual follow-up of cohort members, clinical endpoints ascertainment, study coordination activities, maintenance of the database and biosp75N92020D00001 · NHLBI · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, ROBYN LEAGH · 2020 to 2025
$17.2M
CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5M
MECHANISMS OF HYPERTENSION AND CARDIOVASCULAR DISEASEST32HL007457 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Martin E Young · 1985 to 2026
$8.6M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00005 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2020 to 2025
$5.1M
Whole genome sequences in individuals to comprehensively characterize the genetic mechanisms of dyslipidemiasR01HL142711 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Satoshi Koyama, Gina Marie Peloso · 2019 to 2026
$4.7M
TO EXERCISE OPTION PERIOD ONE (1) FOR TASK AREA A - MESA CORE OPERATIONS, FIELD CENTER.75N92020D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI SIEGEL, JONATHAN H · 2020 to 2025
$4.5M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI PANKOW, JAMES S · 2020 to 2025
$4.4M
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1 TR001881NHLBI NIH HHS 75N92020D00001NHLBI NIH HHS 75N92020D00002NHLBI NIH HHS 75N92020D00003NHLBI NIH HHS 75N92020D00004NHLBI NIH HHS 75N92020D00005NHLBI NIH HHS 75N92020D00006NHLBI NIH HHS 75N92020D00007NHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS K23 HL146887NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL105756NHLBI NIH HHS R01 HL142711NHLBI NIH HHS R01 HL160982NHLBI NIH HHS R01 HL163081NHLBI NIH HHS R01 HL163852NHLBI NIH HHS T32 HL007457NIDDK NIH HHS P30 DK063491
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Risk ScoreHypertensionBlood PressureFemaleHumansMaleRisk FactorsSex Characteristicsblood pressurehypertensionsex-differencestrajectory

Identifiers

PMID38372177
PMCPMC11021155

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.