Evidence map›Paper›PMID 38371782›Full record

ArticleACS omega2024

Co-Delivery of Naringin and Ciprofloxacin by Oleic Acid Lipid Core Encapsulated in Carboxymethyl Chitosan/Alginate Nanoparticle Composite for Enhanced Antimicrobial Activity.

Tahani M Almeleebia, Md Habban Akhter, Habibullah Khalilullah, Mohammad Akhlaquer Rahman, Sarfaraz Ahmad, Nawazish Alam, Md Sajid Ali, Gyas Khan, Ibrahim Mufadhi M Alanazi, Naiyer Shahzad and 1 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Tahani M AlmeleebiaDepartment of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha 61421, Saudi Arabia.
Md Habban AkhterFaculty of Pharmacy, DIT University, Dehradun 248001, India.ORCID https://orcid.org/0000-0001-6278-0370
Habibullah KhalilullahDepartment of Pharmaceutical Chemistry and Pharmacognosy, Unaizah College of Pharmacy, Qassim University, Unaizah 51911, Saudi Arabia.
Mohammad Akhlaquer RahmanDepartment of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, Taif 21974, Saudi Arabia.
Sarfaraz AhmadDepartment of Clinical Pharmacy, College of Pharmacy, Jazan University, Jazan 114, Saudi Arabia.
Nawazish AlamDepartment of Clinical Pharmacy, College of Pharmacy, Jazan University, Jazan 114, Saudi Arabia.
Md Sajid AliDepartment of Pharmaceutics, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.
Gyas KhanDepartment of Pharmacology, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.
Ibrahim Mufadhi M AlanaziDepartment of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah 21421, Saudi Arabia.
Naiyer ShahzadDepartment of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah 21421, Saudi Arabia.
Amnah AlalmaieDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, P.O. Box 62529, Abha61421, Saudi Arabia.
Jazan University · SAKing Khalid University · SAUmm al-Qura University · SADehradun Institute of Technology University · INQassim University · SATaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel combination of antibiotic, ciprofloxacin (CIP) with herbal counterpart naringin (NAR) was encapsulated by an oleic acid lipid core and carboxymethyl chitosan (CM-CS)/Alginate (AG) nanoparticle composite (CIP + NAR-CM-CS/AG-NPs) for improved antimicrobial efficacy of antibiotic. Herein, this study explored the design and preparation of a composite system that enables to deliver both CIP and NAR from the oleic acid lipid core of CM-CS/AG nanoparticles using a nonsolvent ionic gelation technique. The nanoparticles (NPs) were fabricated with improved long-acting antimicrobial activity against

Identifiers

PMID38371782
PMCPMC10870392
OpenAlexW4391472762

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.