Evidence map›Paper›PMID 38371608›Full record

ReviewJournal of clinical and experimental hepatology

"Reduced Size Liver Grafts in Pediatric Liver Transplantation; Technical Considerations".

Mureo Kasahara, Akinari Fukuda, Hajime Uchida, Yusuke Yanagi, Seiichi Shimizu, Ryuji Komine, Toshimasa Nakao, Tasuku Kodama, Harunori Deguchi, Aoi Ninomiya and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Technique Matters! Evolving Techniques in Liver Transplantation.Journal of clinical and experimental hepatology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Mureo KasaharaOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Akinari FukudaOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Hajime UchidaOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Yusuke YanagiOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Seiichi ShimizuOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Ryuji KomineOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Toshimasa NakaoOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Tasuku KodamaOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Harunori DeguchiOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Aoi NinomiyaOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Seisuke SakamotoOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
National Center For Child Health and Development · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver transplantation (LT) has become a vital treatment option for children with end-stage liver disease. Left lateral segment (LLS) grafts are particularly common in split and living donor LT for pediatric patients. However, challenges arise in small infants receiving LLS grafts, primarily due to graft-size mismatches, resulting in "large-for-size" grafts. To overcome this issue, the practice of further reducing grafts from the LLS to diminish graft thickness has been explored. Currently, the indication for reducing the thickness of LLS grafts includes recipients with a body weight (BW) under 5.0 kg, neonates with acute liver failure, or those with metabolic liver disease. At the National Center for Child Health and Development in Tokyo, Japan, among 131 recipients of reduced-size LLS grafts, a remarkable 15-year graft survival rate of 89.9% has been achieved in small infants. This success indicates that with experience and refinement of the technique, there's a trend towards improved graft survival in recipients with reduced-thickness LLS grafts. This advancement underscores the importance of BW-appropriate methods in graft selection to ensure exceptional outcomes in vulnerable pediatric patients in need of LT. These techniques' ongoing development and refinement are crucial in enhancing the survival rates and overall outcomes for these young patients.

Indexed as

graft size matchinglarge-for-size graftliver transplantationliving donor liver transplantationpediatric liver transplantationsmall-for-size graft

Identifiers

PMID38371608
PMCPMC10869284
OpenAlexW4391251975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.