ArticleClinical interventions in aging2024
Trajectory Groups of 72-Hour Heart Rate After Mechanical Thrombectomy and Outcomes.
Article in Clinical interventions in aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Dynamic serum chloride trajectories predict short- and long-term mortality in patients with malignancies: a retrospective cohort study with external validation.Frontiers in oncology · 2026Article
- Outcome of cerebral thrombectomy cannot be predicted by systolic function as long as not all influencing factors are analyzed.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Association between early heart rate trajectories in post-PCI STEMI patients and prognosis after hospital discharge.Annals of medicine · 2025Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background and Purpose: Elevated heart rate (HR) after mechanical thrombectomy (MT) was associated with an increased risk of adverse outcomes. However, optimal HR management after MT remains unclear. This study aimed to identify patient subgroups with distinct HR trajectories after MT and explore their association with outcomes. Methods: Acute ischemic stroke patients undergoing MT therapy were prospectively recruited from July 2020 to December 2022. Their heart rate indicators were collected every hour for 72 hours after MT procedure. Latent variable mixture modeling was used to separate subjects into five groups with distinct HR trajectories. The primary outcome was poor functional outcome (mRS score >2) at 3 months. Additional outcome was all-cause mortality (mRS score = 6) at 3 months. Results: A total of 224 patients with large vessel occlusion were enrolled, with a mean age of 65.2+14.0 years. Eighty-seven patients had a good functional outcome, and 137 patients had a poor functional outcome. Five distinct HR trajectories were observed: low (19.2%), moderate (33.0%), rapidly stabilized HR group (20.5%), persistently high HR group (21.0%), and very high HR group (6.3%). After adjusting for potential confounders, the HR trajectory group was independently associated with poor functional outcome at 3 months ( Conclusion: HR during the first 72 hours after MT may be categorized into distinct trajectory groups, which differ in relation to poor functional outcome event risks. The findings may help to recognize potential candidates for future HR control trials.
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