Evidence map›Paper›PMID 38371491›Full record

ArticleChemistry (Basel, Switzerland)2023

Ratiometric Detection of Zn

Yuting Wu, Whitney Lewis, Jing Luen Wai, Mengyi Xiong, Jiao Zheng, Zhenglin Yang, Chloe Gordon, Ying Lu, Siu Yee New, Xiao-Bing Zhang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Yuting WuDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
Whitney LewisDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
Jing Luen WaiDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Mengyi XiongDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Jiao ZhengDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Zhenglin YangDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
Chloe GordonDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
Ying LuDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
Siu Yee NewSchool of Pharmacy, Faculty of Science and Engineering, University of No0ingham Malaysia, Semenyih, Selangor 43500, Malaysia.
Xiao-Bing ZhangMolecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, China.
Yi LuDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
University of Illinois Urbana-Champaign · USUniversity of Nottingham Malaysia Campus · MYThe University of Texas at Austin · US

Funding

Design and Selection of Novel Metalloenzymes for Biocatalysis, Bioimaging, and Genetic EngineeringR35GM141931 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Yi Lu · 2021 to 2026
$3.5M
NIGMS NIH HHS R35 GM141931
6 · The paper itself

Abstract

While fluorescent sensors have been developed for monitoring metal ions in health and diseases, they are limited by the requirement of an excitation light source that can lead to photobleaching and a high autofluorescence background. To address these issues, bioluminescence resonance energy transfer (BRET)-based protein or small molecule sensors have been developed; however, most of them are not highly selective nor generalizable to different metal ions. Taking advantage of the high selectivity and generalizability of DNAzymes, we report herein DNAzyme-based ratiometric sensors for Zn

Indexed as

bioluminescence resonance energy transfer (BRET)DNA machines for biosensingDNAzymemetal detection

Identifiers

PMID38371491
PMCPMC10874629
OpenAlexW4385650063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.