Evidence map›Paper›PMID 38371469›Full record

ArticleACG case reports journal2024

Cytokine Release Syndrome-Associated Colitis: Insights From a Case of Rituximab-Induced Pancolitis.

Fnu Vikash, Sindhu Vikash, Michael Mintz, Suzanne Elshafey, Daniel Kim, David Wan

Open access · diamondAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fnu VikashDepartment of Medicine, Albert Einstein College of Medicine/Jacobi Medical Center, Bronx, NY.
Sindhu VikashDepartment of Medicine, Albert Einstein College of Medicine/Jacobi Medical Center, Bronx, NY.
Michael MintzDepartment of Gastroenterology, Weill Cornell Medicine, Manhattan, NY.
Suzanne ElshafeyDepartment of Gastroenterology, Weill Cornell Medicine, Manhattan, NY.
Daniel KimDepartment of Gastroenterology, Weill Cornell Medicine, Manhattan, NY.
David WanDepartment of Gastroenterology, Weill Cornell Medicine, Manhattan, NY.
Weill Cornell Medicine · USJacobi Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rituximab (RTX), a widely used monoclonal antibody for hematologic malignancies and rheumatologic disorders, is known for infusion-related reactions. However, its potential to induce colitis is often overlooked. We present an 85-year-old woman with chronic lymphocytic leukemia experiencing severe adverse effects during her fourth RTX infusion, including abdominal pain, hypotension, and bright red blood per rectum. Computed tomography of the abdomen and pelvis with contrast revealed pancolonic mural wall thickening without perforation. Prompt treatment with vasopressors and intravenous fluids led to symptom resolution within 24 hours. We highlighted the importance of recognizing RTX-induced colitis and discussed and depicted immunological dysregulation mechanisms involved.

Indexed as

bright red blood per rectumcolitiscolonoscopycytokine release syndromerituximab

Identifiers

PMID38371469
PMCPMC10871758
OpenAlexW4391887452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.