Evidence map›Paper›PMID 38371361›Full record

ArticleResearch and reports in tropical medicine2024

A Cross Sectional Study on the Bidirectional Interactions Between Leptospirosis and HIV Infection Among Patients from Maputo Central Hospital, Mozambique.

Isac Rodrigues Comia, Leonardo Manuel, Regina Daniel Miambo, Awa Abdul Carimo, Percílio da Floca Manjate, Ana Edith Maholela, Lucas Raimundo Banze, Titos Paulo Buene, Noémia Nhancupe, Irina M Sousa and 4 more

Open access · goldAbstract read
In one paragraph

Article in Research and reports in tropical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Seroprevalence and Risk Factors forResearch and reports in tropical medicine · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Isac Rodrigues Comia *Department of Research and Extension, Faculty of Health Sciences, Lúrio University, Nampula, Mozambique.ORCID 0009-0004-8356-8802
Leonardo Manuel *Department of Research and Extension, Faculty of Health Sciences, Lúrio University, Nampula, Mozambique.
Regina Daniel MiamboMozambique Institute for Health Education and Research (MIHER), Maputo, Mozambique.ORCID 0000-0002-0814-4231
Awa Abdul CarimoMozambique Institute for Health Education and Research (MIHER), Maputo, Mozambique.ORCID 0000-0003-1599-4856
Percílio da Floca ManjateMozambique Institute for Health Education and Research (MIHER), Maputo, Mozambique.
Ana Edith MaholelaMozambique Institute for Health Education and Research (MIHER), Maputo, Mozambique.
Lucas Raimundo BanzeDepartment of Microbiology, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Titos Paulo BueneDepartment of Microbiology, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Noémia NhancupeDepartment of Microbiology, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.ORCID 0009-0004-3433-5877
Irina M SousaMozambique Institute for Health Education and Research (MIHER), Maputo, Mozambique.ORCID 0000-0002-2515-9806
Constance A BensonDepartment of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego, CA, USA.
Robert T SchooleyDepartment of Medicine, Division of Infectious Diseases, University of California, San Diego, CA, USA.
Jahit SacarlalDepartment of Microbiology, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.ORCID 0000-0003-1059-217X
Emília Virgínia NoormahomedDepartment of Microbiology, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.ORCID 0000-0001-8874-1900
Eduardo Mondlane University · MZUniversity of California San Diego · USMaputo Central Hospital · MZ

Funding

The University Eduardo Mondlane/UCSD Health-Professional Education Partnership InitiativeR25TW011216 · FIC · EDUARDO MONDLANE UNIVERSITY · PI NOORMAHOMED, EMILIA VIRGINIA · 2018 to 2022
$3.2M
Enhancing Advanced Biomedical Training in MozambiqueD43TW010568 · FIC · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NOORMAHOMED, EMILIA VIRGINIA, SCHOOLEY, ROBERT TURNER · 2017 to 2021
$1.5M
FIC NIH HHS D43 TW010568FIC NIH HHS R25 TW011216
6 · The paper itself

Abstract

Introduction: This study aims to determine the baseline seroprevalence of leptospirosis, a zoonotic and neglected disease, in people living with HIV (PWH) in Maputo, Mozambique, and to evaluate the relationship between selected HIV-related factors that might influence risk of coinfection with leptospirosis, such as degree of immunosuppression, as assessed by CD4 cell count, World Health Organization (WHO) HIV/AIDS clinical stage and antiretroviral therapy (ART) intake. Methods: This was a descriptive cross-sectional analysis of 157 PWH, aged over 18 years old, admitted to the Maputo Central Hospital, in Maputo, Mozambique, between March 2020 and October 2021. The study participants were recruited as a convenience sample regardless of the reasons for their admission. We collected sociodemographic and clinical data, including ART and WHO HIV/AIDS clinical stage, and blood for CD4 cell count and detection of Results: Participants were aged 18 to 72 years (median age 39 years; SD ± 10.5), the majority were female 100 (63.7%), from urban areas 138 (87.9%), with secondary-level education 80 (51%). The overall seroprevalence of Conclusion: Our study confirmed that

Indexed as

co-infection Leptospira and HIVLeptospira IgGleptospirosisMozambique

Identifiers

PMID38371361
PMCPMC10871144
OpenAlexW4391752642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.