Evidence map›Paper›PMID 38371310›Full record

ArticleInternational journal of cardiology. Heart & vasculature2024

Utility of native T1 mapping and myocardial extracellular volume fraction in patients with nonischemic dilated cardiomyopathy: A systematic review and meta-analysis.

Michael Tao, Simrat Dhaliwal, Dhairyasheel Ghosalkar, Siyuan Sheng, Neda Dianati-Maleki, Edlira Tam, Tahmid Rahman, Noelle Mann, Smadar Kort

Abstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. One Syndrome, Many Faces: A Unified Perspective on Heart Failure Phenotypes.International journal of molecular sciences · 2025
    Review
  7. Review
  8. The relationship between native T1 and mortality in patients requiring maintenance haemodialysis, using cardiac magnetic resonance imaging.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael TaoDepartment of Medicine, Division of Cardiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Simrat DhaliwalDepartment of Medicine, Division of Cardiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Dhairyasheel GhosalkarDepartment of Medicine, Division of Cardiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Siyuan ShengDepartment of Medicine, Division of Cardiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Neda Dianati-MalekiDepartment of Medicine, Division of Cardiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Edlira TamDepartment of Medicine, Division of Cardiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Tahmid RahmanDepartment of Medicine, Division of Cardiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Noelle MannDepartment of Medicine, Division of Cardiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Smadar KortDepartment of Medicine, Division of Cardiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac magnetic resonance imaging (CMR) based T1 mapping and extracellular volume fraction (ECV) are powerful tools for identifying myocardial fibrosis. This systematic review and Methods: A literature search was conducted for studies reporting on use of CMR-based native T1 mapping and ECV measurement in NICM patients and their association with major adverse cardiac events (MACE), ventricular arrhythmias (VAs), and left ventricular reverse remodeling (LVRR). Databases searched included: Ovid MEDLINE, EMBASE, Web of Science, and Google Scholar. The search was not restricted to time or publication status. Results: Native T1 and ECV were significantly higher in NICM patients compared to controls (MD 78.80, 95 % CI 50.00, 107.59; p < 0.01; MD 5.86, 95 % CI 4.55, 7.16; p < 0.01). NICM patients who experienced MACE had higher native T1 and ECV (MD 52.87, 95 % CI 26.59, 79.15; p < 0.01; MD 6.03, 95 % CI 3.79, 8.26; p < 0.01). There was a non-statistically significant trend toward higher native T1 time in NICM patients who experienced VAs. NICM patients who were poor treatment responders had higher baseline native T1 and ECV (MD 40.58, 95 % CI 12.90, 68.25; p < 0.01; MD 3.29, 95 % CI 2.25, 4.33; p < 0.01). Conclusions: CMR-based native T1 and ECV quantification may be useful tools for risk stratification of patients with NICM. They may provide additional diagnostic utility in combination with LGE, which poorly characterizes fibrosis in patients with diffuse myocardial involvement.

Indexed as

CMRECVHeart FailureOutcomesPrognosisT1

Identifiers

PMID38371310
PMCPMC10873728

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.