ArticleInternational journal of ophthalmology2024
One-year results for myopia control of orthokeratology with different back optic zone diameters: a randomized trial using a novel multispectral-based topographer.
Article in International journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- The effectiveness of red-light therapy on myopia control depends on its direct effect: a mediation analysis.Journal of translational medicine · 2025Trial
- Low-Dose Atropine and Other Interventions for Pediatric Myopia: A Systematic Review and Bayesian Network Meta-analysis of Efficacy and Post-treatment Outcomes.Ophthalmology and therapy · 2026Review
- Correlation between retinal defocus distribution and axial growth in myopic children wearing orthokeratology lenses.BMC ophthalmology · 2026Article
- Design-Dependent Myopia Control in Orthokeratology: Spherical Versus Aspherical Back Optic Zone Profiles.Bioengineering (Basel, Switzerland) · 2026Article
- Effectiveness of orthokeratology plus vision therapy for controlling myopia progression in children.American journal of translational research · 2026Article
- Ocular Dimensional Changes After 12 Months of Orthokeratology and Single-Vision Spectacle Use: A Three-Dimensional Magnetic Resonance Imaging Study.Clinical optometry · 2026Article
- IMI-Interventions for Controlling Myopia Onset and Progression 2025.Investigative ophthalmology & visual science · 2025Review
- Peripheral Defocus in Orthokeratology Myopia Correction: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Myopia control efficacy of peripheral defocus modifying spectacle lenses in children and adolescents: a Meta-analysis.International journal of ophthalmology · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo present the 1-year results of a prospective cohort study investigating the efficacy, potential mechanism, and safety of orthokeratology (ortho-k) with different back optic zone diameters (BOZD) for myopia control in children.
methodsThis randomized clinical study was performed between Dec. 2020 and Dec. 2021. Participants were randomly assigned to three groups wearing ortho-k: 5 mm BOZD (5-MM group), 5.5 mm BOZD (5.5-MM group), and 6 mm BOZD (6-MM group). The 1-year data were recorded, including axial length, relative peripheral refraction (RPR, measured by multispectral refractive topography, MRT), and visual quality. The contrast sensitivity (CS) was evaluated by CSV-1000 instrument with spatial frequencies of 3, 6, 12, and 18 cycles/degree (c/d); the corneal higher-order aberrations (HOAs) were measured by iTrace aberration analyzer. The one-way ANOVA was performed to assess the differences between the three groups. The correlation between the change in AL and RPR was calculated by Pearson's correlation coefficient.
resultsThe 1-year results of 20, 21, and 21 subjects in the 5-MM, 5.5-MM, and 6-MM groups, respectively, were presented. There were no statistical differences in baseline age, sex, or ocular parameters between the three groups (all
conclusionOrtho-k with 5 mm BOZD can control myopia progression more effectively. The mechanism may be associated with greater myopic shifts in RPR.
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Registered trials
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