Evidence map›Paper›PMID 38371212›Full record

ReviewBJUI compass2024

One-year outcomes after prostate artery embolization versus laser enucleation: A network meta-analysis.

Ansh Bhatia, Joao Gabriel Porto, Aneesha Maini, Deepak Langade, Thomas R W Herrmann, Hemendra Navinchandra Shah, Shivank Bhatia

Open access · goldAbstract readReview
In one paragraph

Review in BJUI compass, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Ansh BhatiaDepartment of Interventional Radiology, Miller School of Medicine University of Miami Miami Florida USA.ORCID https://orcid.org/0000-0001-6131-4837
Joao Gabriel PortoDepartment of Urology University of Miami Miami Florida USA.ORCID https://orcid.org/0000-0002-6495-1054
Aneesha MainiSchool of Medicine Georgetown University Washington District of Columbia USA.ORCID https://orcid.org/0000-0002-6320-6757
Deepak LangadeSchool of Medicine DY Patil University Navi Mumbai India.ORCID https://orcid.org/0000-0001-8382-5216
Thomas R W HerrmannDepartment of Urology Switzerland Urology Spital Thurgau AG (STGAG) Frauenfeld Switzerland.
Hemendra Navinchandra ShahDepartment of Urology, Desai Sethi Urology Institute, Miller School of Medicine University of Miami Miami Florida USA.ORCID https://orcid.org/0000-0002-4273-5502
Shivank BhatiaDepartment of Interventional Radiology, Miller School of Medicine University of Miami Miami Florida USA.ORCID https://orcid.org/0000-0001-6610-2550
University of Miami · USD.Y. Patil University · INGeorgetown University · USSpital Thurgau (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although holmium laser enucleation (HoLEP) is considered a size-independent procedure for treatment of an enlarged prostate, prostate artery embolization (PAE) is emerging as an alternative modality to treat moderate and large benign prostatic hyperplasia. This study aims to compare the early post-operative and short-term efficacy of PAE and HoLEP. Methods: PubMed, Cochrane Library and EMBASE databases were searched. Network meta-analysis was performed following PRISMA-N-guidelines. Post-operative parameters analysed include international prostate symptom score (IPSS), quality of life (QOL), post-void residual urine (PVR), maximal uroflow rate (Qmax) and serious adverse events (SAE). Random effects model calculated weighted mean differences (WMD). If 95%CI crossed the line of no effect (WMD = 0), evidence indicated no statistically significant difference between treatments compared. Results: Qualitative and quantitative syntheses included 20 and 18 studies with 1991 and 1606 patients, respectively. At 3 months, there was no statistically significant difference between PAE and HoLEP in IPSS score improvement [WMD: -2.21: 95%CI: (-10.20, 5.78), favouring PAE], QoL score improvement [WMD: -0.22:95%CI: (-1.75, 1.32), favouring PAE] and PVR improvement [WMD: 26.97: 95%CI: (-59.53, 113.48), favouring HoLEP]. However, PAE was found inferior to HoLEP for Qmax improvement [WMD: 8.47, 95%CI: (2.89, 14.05), favouring HoLEP]. At 1-year follow-up, there was no statistically significant was found between PAE and HoLEP for IPSS score improvement [WMD:6.03, 95%CI: (-1.30, 13.35)], QoL score improvement [WMD: 0.03, 95%CI: (-1.19, 1.25)], PVR improvement [WMD:4.11, 95%CI: (-32.31, 40.53)] and Qmax improvement [WMD:2.60, 95%CI: (-2.20, 7.41)] with all differences favouring HoLEP. PAE was superior to HoLEP for SAE [PAE vs. HoLEP-OR: 0.68, 95%CI: (0.25, 1.37)]. Conclusion: HoLEP was superior to PAE at 3 months for Qmax improvement. There was no significant difference in IPSS, QoL, PVR and Qmax improvement at 1 year between PAE and HoLEP. PAE was also associated with lesser SAE compared to HoLEP. Studies on the long-term outcome of PAE are needed to establish the durability of early outcomes after PAE.

Indexed as

benign prostatic hyperplasiacomplicationsendoscopic enucleation of prostateenlarged prostateholmium laser enucleation of prostateminimally invasive surgical therapyprostate artery embolization

Identifiers

PMID38371212
PMCPMC10869668
OpenAlexW4387972598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.