ArticleCureus2024
The mRNA Vaccination Rate Is Negatively and the Proportion of Elderly Individuals Is Positively Associated With the Excess Mortality Rate After 2020 in Japan.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Unraveling Rising Mortality: Statistical Insights from Japan and International Comparisons.Healthcare (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact of mRNA vaccines on excess mortality during the COVID-19 pandemic in Japan is not clear. This study aimed to verify the explanatory factors of excess mortality rate using officially published data by government and research institutions.
methodsMultiple regression analysis was performed using the excess mortality rate in Japanese prefectures as the objective variable and the mRNA vaccination rate, proportion of elderly individuals in the population, number of physicians per population, and medical expenditure per person as explanatory variables.
resultsFrom July 2021 to April 2023, the independent determinants of the excess mortality rate were as follows: proportion of elderly individuals (regression coefficient (B) = 0.0097, p < 0.001), partial vaccination rate (B = -0.0034, p = 0.048), proportion of elderly individuals (B = 0.010, p < 0.001), and third-shot vaccination rate (B = -0.0025, p < 0.046). The stepwise method did not essentially change the results. However, the p-values were smaller. The other two indicators were not associated with the excess mortality rate.
conclusionsmRNA vaccination was associated with a lower excess mortality in Japan during the period, whereas the proportion of elderly individuals was associated with an increase in excess mortality. Thus, a policy of aggressive recommendations for mRNA vaccination is justified.
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