Evidence map›Paper›PMID 38370791›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Hereditary breast cancer next-generation sequencing (NGS) panel evaluation in the south region of Brazil: a novel

Cesar Augusto B Duarte, Carlos Alberto Dos Santos, Cristine Domingues D de Oliveira, Cleverton César Spautz, Laura Masami Sumita, Sueli Massumi Nakatani

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cesar Augusto B DuarteResearch and Development Division, Genoprimer Diagnóstico Molecular, Curitiba, Paraná, Brazil.ORCID 0009-0004-8864-3357
Carlos Alberto Dos SantosClinimol Diagnóstico Molecular, Molecular Biology Clinical Laboratory, São Paulo, São Paulo, Brazil.
Cristine Domingues D de OliveiraClinimol Diagnóstico Molecular, Molecular Biology Clinical Laboratory, São Paulo, São Paulo, Brazil.
Cleverton César SpautzHospital Nossa Senhora das Graças, Department of Surgery, Curitiba, Paraná, Brazil.
Laura Masami SumitaClinimol Diagnóstico Molecular, Molecular Biology Clinical Laboratory, São Paulo, São Paulo, Brazil.
Sueli Massumi NakataniResearch and Development Division, Genoprimer Diagnóstico Molecular, Curitiba, Paraná, Brazil.
Hospital Nossa Senhora das Graças · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this article, we delineate a loosely selected cohort comprising patients with a history of early-onset breast cancer and/or a familial occurrence of cancer. The aim of this study was to gain insights into the presence of breast cancer-related gene variants in a population from a micro-region in southern Brazil, specifically the Metropolitan Region of Curitiba. This area exhibits a highly genetically mixed population, mirroring the general characteristics of the Brazilian people. Comprehensive next-generation sequencing (NGS) multigene panel testing was conducted, involving the evaluation of twelve patients. Two pathogenic variants and one candidate pathogenic variant were identified:

Identifiers

PMID38370791
PMCPMC10871466
OpenAlexW4391694668

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.