Evidence map›Paper›PMID 38370754›Full record

ArticlebioRxiv : the preprint server for biology2024

Temporal dynamics of BMP/Nodal ratio drive tissue-specific gastrulation morphogenesis.

Alyssa A Emig, Megan Hansen, Sandra Grimm, Cristian Coarfa, Nathan D Lord, Margot Kossmann Williams

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alyssa A EmigCenter for Precision Environmental Health and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.
Megan HansenCenter for Precision Environmental Health and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.
Sandra GrimmCenter for Precision Environmental Health and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.
Cristian CoarfaCenter for Precision Environmental Health and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.
Nathan D LordDepartment of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA.
Margot Kossmann WilliamsCenter for Precision Environmental Health and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.
Baylor College of Medicine · USUniversity of Pittsburgh · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9M
Initiative for Maximizing Student Development (IMSD) ProgramR25GM056929 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PEREIRA, FRED A · 1998 to 2023
$12.4M
Training in Precision Environmental Health SciencesT32ES027801 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2018 to 2026
$2.8M
Molecular drivers of tissue-specific morphogenetic programsR01HD104784 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Margot L.K. Williams · 2022 to 2026
$2.2M
Defining Direct and Indirect Roles of Nodal Signaling in Convergence & ExtensionR00HD091386 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI WILLIAMS, MARGOT L.K. · 2020 to 2022
$680k
Mechanisms of Morphogen Transport and Interpretation in Early EmbryosR00HD097297 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LORD, NATHAN DALE · 2020 to 2023
$619k
Baylor College of Medicine Initiative for Maximizing Student DevelopmentT32GM152777 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PANGAS, STEPHANIE A., PEREIRA, FRED A · 2024 to 2024
$547k
Regulation of neuroectoderm morphogenesis by Nodal signaling programsF31GM149166 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI EMIG, ALYSSA NICOLE · 2023 to 2024
$81k
NCI NIH HHS P30 CA125123NICHD NIH HHS R00 HD091386NICHD NIH HHS R00 HD097297NICHD NIH HHS R01 HD104784NIEHS NIH HHS T32 ES027801NIGMS NIH HHS F31 GM149166NIGMS NIH HHS R25 GM056929NIGMS NIH HHS T32 GM152777
6 · The paper itself

Abstract

Anteroposterior (AP) elongation of the vertebrate body plan is driven by convergence and extension (C&E) gastrulation movements in both the mesoderm and neuroectoderm, but how or whether molecular regulation of C&E differs between tissues remains an open question. Using a zebrafish explant model of AP axis extension, we show that C&E of the neuroectoderm and mesoderm can be uncoupled

Indexed as

BMPConvergent extensionGastrulationMorphogenesisNodalZebrafish

Identifiers

PMID38370754
PMCPMC10871350
OpenAlexW4391729502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.