Evidence map›Paper›PMID 38370739›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Daniel S Levic, Donna Niedzwiecki, Apoorva Kandakatla, Norah S Karlovich, Arjun Juneja, Jieun Park, Christina Stolarchuk, Shanté Adams, Jason R Willer, Matthew R Schaner and 11 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Updated by
    2024
5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Daniel S LevicDepartment of Cell Biology, Duke University, Durham, NC, USA.ORCID 0000-0003-0240-5178
Donna NiedzwieckiDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Apoorva KandakatlaDivision of Gastroenterology, Department of Medicine, Duke University, Durham, NC, USA.
Norah S KarlovichDivision of Gastroenterology, Department of Medicine, Duke University, Durham, NC, USA.
Arjun JunejaDepartment of Cell Biology, Duke University, Durham, NC, USA.
Jieun ParkDepartment of Cell Biology, Duke University, Durham, NC, USA.
Christina StolarchukDivision of Gastroenterology, Department of Medicine, Duke University, Durham, NC, USA.
Shanté AdamsCenter for Human Disease Modeling, Duke University Medical Center, Durham, NC, USA.
Jason R WillerCenter for Human Disease Modeling, Duke University Medical Center, Durham, NC, USA.
Matthew R SchanerCenter for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Grace LianCenter for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Caroline BeasleyCenter for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Lindsay MarjoramDepartment of Cell Biology, Duke University, Durham, NC, USA.
Ann D FlynnDivision of Gastroenterology, Hepatology and Nutrition, University of Utah Health, Salt Lake City, Utah.
John F ValentineDivision of Gastroenterology, Hepatology and Nutrition, University of Utah Health, Salt Lake City, Utah.
Jane E OnkenDivision of Gastroenterology, Department of Medicine, Duke University, Durham, NC, USA.
Shehzad Z SheikhCenter for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Erica E DavisDepartment of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Kimberley J EvasonHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Katherine S GarmanDivision of Gastroenterology, Department of Medicine, Duke University, Durham, NC, USA.ORCID 0000-0001-7763-8465
Michel BagnatDepartment of Cell Biology, Duke University, Durham, NC, USA.
Duke University · USUniversity of North Carolina at Chapel Hill · USUniversity of Utah · USDuke Medical Center · USNorthwestern University · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI KATHARINE S ULLMAN · 1986 to 2026
$72.6M
PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Temitope O. Keku · 1985 to 2026
$30.5M
Role of IL-10 in APC Regulation of Protective vs. Pathogenic T Cell Responses toP01DK094779 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHEIKH, SHEHZAD Z. · 2013 to 2023
$17.9M
DUKE TRAINING GRANT IN DIGESTIVE DISEASES AND NUTRITIONT32DK007568 · NIDDK · DUKE UNIVERSITY · PI Katherine Garman, Rodger A. Liddle · 1988 to 2026
$5.6M
Developmental regulation of epithelial polarization by pre-mRNA splicingR01DK132120 · NIDDK · DUKE UNIVERSITY · PI Michel Bagnat · 2023 to 2026
$1.8M
Genetic and Epigenetic Regulation of Intestinal InflammationR01DK113123 · NIDDK · DUKE UNIVERSITY · PI BAGNAT, MICHEL · 2018 to 2021
$1.7M
Integrative Genetic and Genomic Analyses in the Inflammatory Bowel DiseaseR01DK104828 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FUREY, TERRENCE S., SHEIKH, SHEHZAD Z. · 2016 to 2018
$901k
Epigenetic Regulation of Intestinal InflammationF32DK098885 · NIDDK · DUKE UNIVERSITY · PI MARJORAM, LINDSAY T. · 2013 to 2015
$88k
NCI NIH HHS P30 CA042014NIDDK NIH HHS F32 DK098885NIDDK NIH HHS P01 DK094779NIDDK NIH HHS P30 DK034987NIDDK NIH HHS R01 DK104828NIDDK NIH HHS R01 DK113123NIDDK NIH HHS R01 DK132120NIDDK NIH HHS T32 DK007568
6 · The paper itself

Abstract

Background and aims: Inflammatory Bowel Diseases (IBD) are chronic inflammatory conditions influenced heavily by environmental factors. DNA methylation is a form of epigenetic regulation linking environmental stimuli to gene expression changes and inflammation. Here, we investigated how DNA methylation of the Methods: We obtained mucosal biopsies from 200 participants (133 IBD and 67 controls) and analyzed Results: Conclusions: Our study reveals an association of

Indexed as

Anit-TNF ResponseEpigeneticsInflammatory Bowel DiseaseMethylation

Identifiers

PMID38370739
PMCPMC10871362
OpenAlexW4391558280

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.