Evidence map›Paper›PMID 38370642›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Cumulus: A federated EHR-based learning system powered by FHIR and AI.

Andrew J McMurry, Daniel I Gottlieb, Timothy A Miller, James R Jones, Ashish Atreja, Jennifer Crago, Pankaja M Desai, Brian E Dixon, Matthew Garber, Vladimir Ignatov and 9 more

Open access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Andrew J McMurryComputational Health Informatics Program, Boston Children's Hospital, Boston, MA.ORCID 0000-0001-5604-0704
Daniel I GottliebComputational Health Informatics Program, Boston Children's Hospital, Boston, MA.ORCID 0000-0003-4658-2854
Timothy A MillerComputational Health Informatics Program, Boston Children's Hospital, Boston, MA.ORCID 0000-0003-4513-403X
James R JonesComputational Health Informatics Program, Boston Children's Hospital, Boston, MA.ORCID 0009-0001-2940-3634
Ashish AtrejaDepartment of Health Information Technology, UC Davis Health, Rancho Cordova, CA.ORCID 0000-0002-0628-4417
Jennifer CragoCenter for Biomedical Informatics, Regenstrief Institute, Indianapolis, IN.
Pankaja M DesaiDepartment of Internal Medicine, Rush University Medical Center, Chicago IL.ORCID 0000-0002-0904-5905
Brian E DixonCenter for Biomedical Informatics, Regenstrief Institute, Indianapolis, IN.ORCID 0000-0002-1121-0607
Matthew GarberComputational Health Informatics Program, Boston Children's Hospital, Boston, MA.ORCID 0009-0008-9838-8416
Vladimir IgnatovComputational Health Informatics Program, Boston Children's Hospital, Boston, MA.ORCID 0009-0009-5743-1825
Lyndsey A KirchnerCDC Foundation, Atlanta, GA.
Philip R O PayneDepartment of Medicine, Washington University in St. Louis, St. Louis, MO.ORCID 0000-0002-9532-2998
Anil J SaldanhaDepartment of Health Innovation, Rush University Medical Center, Chicago, IL.ORCID 0009-0007-1019-7862
Prabhu R V ShankarDepartment of Health Information Technology, UC Davis Health, Rancho Cordova, CA.ORCID 0000-0001-9909-8527
Yauheni V SoladDepartment of Health Information Technology, UC Davis Health, Rancho Cordova, CA.ORCID 0000-0002-8963-5664
Elizabeth A SprouseDouble Lantern Informatics, Atlanta, GA.ORCID 0009-0003-2904-2319
Michael TerryComputational Health Informatics Program, Boston Children's Hospital, Boston, MA.ORCID 0009-0001-2219-3208
Adam B WilcoxDepartment of Medicine, Washington University in St. Louis, St. Louis, MO.ORCID 0000-0002-6305-735X
Kenneth D MandlComputational Health Informatics Program, Boston Children's Hospital, Boston, MA.ORCID 0000-0002-9781-0477
Boston Children's Hospital · USRegenstrief Institute · USRush University Medical Center · USUC Davis Health · USWashington University in St. Louis · USCDC Foundation · USDepartment of Public Health · US

Funding

Instrumenting the Delivery System for a Genomics Research Information CommonsU01TR002623 · NCATS · BOSTON CHILDREN'S HOSPITAL · PI MANDL, KENNETH D. · 2019 to 2024
$8.6M
Translating Scientific Evidence into Practice using Digital Medicine and Electronic Patient Reported OutcomesU01TR002997 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ATREJA, ASHISH, RIZK, MAGED · 2020 to 2023
$4.7M
Leveraging Electronic Health Data to Assess the Burden of Diabetes among Young AdultsU18DP006500 · DP · INDIANA UNIVERSITY INDIANAPOLIS · PI DIXON, BRIAN E., MENDONCA, ENEIDA A · 2020 to 2024
$1.4M
NCATS NIH HHS U01 TR002623NCATS NIH HHS U01 TR002997NCCDPHP CDC HHS U18 DP006500OSTLTS CDC HHS NU38OT000286
6 · The paper itself

Abstract

Objective: To address challenges in large-scale electronic health record (EHR) data exchange, we sought to develop, deploy, and test an open source, cloud-hosted app 'listener' that accesses standardized data across the SMART/HL7 Bulk FHIR Access application programming interface (API). Methods: We advance a model for scalable, federated, data sharing and learning. Cumulus software is designed to address key technology and policy desiderata including local utility, control, and administrative simplicity as well as privacy preservation during robust data sharing, and AI for processing unstructured text. Results: Cumulus relies on containerized, cloud-hosted software, installed within a healthcare organization's security envelope. Cumulus accesses EHR data via the Bulk FHIR interface and streamlines automated processing and sharing. The modular design enables use of the latest AI and natural language processing tools and supports provider autonomy and administrative simplicity. In an initial test, Cumulus was deployed across five healthcare systems each partnered with public health. Cumulus output is patient counts which were aggregated into a table stratifying variables of interest to enable population health studies. All code is available open source. A policy stipulating that only aggregate data leave the institution greatly facilitated data sharing agreements. Discussion and Conclusion: Cumulus addresses barriers to data sharing based on (1) federally required support for standard APIs (2), increasing use of cloud computing, and (3) advances in AI. There is potential for scalability to support learning across myriad network configurations and use cases.

Indexed as

Electronic health recordfederated networksinteroperabilitypublic health

Identifiers

PMID38370642
PMCPMC10871375
OpenAlexW4391579786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.