Evidence map›Paper›PMID 38370606›Full record

ArticleInternational medical case reports journal2024

HCV Reactivation in a Patient with Hepatocellular Carcinoma Due to Sorafenib: A Case Report.

Jun Cheng, Jinjin Pan, Dongmei Zhao, Xuejiao Ma, Qiulin Sun, Jiabin Li

Open access · goldAbstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jun Cheng *Department of Infectious Disease, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Jinjin Pan *Department of Infectious Disease, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Dongmei ZhaoDepartment of Infectious Disease, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Xuejiao MaDepartment of Infectious Disease, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Qiulin SunDepartment of Infectious Disease, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Jiabin LiDepartment of Infectious Disease, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Anhui Medical University · CNFirst Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global prevalence of hepatitis C virus (HCV) infection is approximately 3%, with a post-infection chronicity rate of up to 50%-85%. HCV reactivation can occur when anti-HCV positive individuals receive antineoplastic therapy. In this study, we report a case of an anti-HCV positive patient with negative HCV RNA after 12 weeks of direct antiviral therapy. Two months later, sorafenib was used to treat hepatocellular carcinoma, and HCV reactivation occurred after 8 months of the treatment. HCV RNA was negative after 12 weeks of antiviral treatment with Sofosbuvir-velpatasvir. We also discussed the mechanism of HCV reactivation caused by sorafenib and the antiviral treatment regimen after HCV reactivation with the relevant literature.

Indexed as

anti-HCV therapyHCV-RNAhepatocellular carcinomareactivationsorafenib

Identifiers

PMID38370606
PMCPMC10870992
OpenAlexW4391751569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.