Evidence map›Paper›PMID 38370475›Full record

ArticleFrontiers in pharmacology2024

Mohamed A A Orabi, Mohamed E Abouelela, Faten M M Darwish, Mohamed S A Abdelkader, Bakheet E M Elsadek, Ahmed Abdullah Al Awadh, Mohammed Merae Alshahrani, Abdulaziz Hassan Alhasaniah, Nayef Aldabaan, Reda A Abdelhamid

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. The effect of flavonoids on the doxorubicin efficacy in cancer treatment.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Mohamed A A OrabiDepartment of Pharmacognosy, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Mohamed E AbouelelaDepartment of Pharmacognosy, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Faten M M DarwishDepartment of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Mohamed S A AbdelkaderDepartment of Pharmacognosy, Faculty of Pharmacy, Sohag University, Sohag, Egypt.
Bakheet E M ElsadekDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.
Ahmed Abdullah Al AwadhDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University, Najran, Saudi Arabia.
Mohammed Merae AlshahraniDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University, Najran, Saudi Arabia.
Abdulaziz Hassan AlhasaniahDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University, Najran, Saudi Arabia.
Nayef AldabaanDepartment of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Reda A AbdelhamidDepartment of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.
Najran University · SAAl-Azhar University · EGAssiut University · EGSohag University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is a prevalent cancer worldwide. Late-stage detection, ineffective treatments, and tumor recurrence contribute to the low survival rate of the HCC. Conventional chemotherapeutic drugs, like doxorubicin (DOX), are associated with severe side effects, limited effectiveness, and tumor resistance. To improve therapeutic outcomes and minimize these drawbacks, combination therapy with natural drugs is being researched. Herein, we assessed the antitumor efficacy of

Indexed as

AFP-l3antitumorCeiba pentandradietary flavonoidsdoxorubicinhepatocellular carcinomain vivoUHPLC-Q-ToF-MS/MS

Identifiers

PMID38370475
PMCPMC10871037
OpenAlexW4391486678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.