Evidence map›Paper›PMID 38370447›Full record

ArticleBrain communications2024

Diffusion weighted magnetic resonance spectroscopy revealed neuronal specific microstructural alterations in Alzheimer's disease.

Nicola Spotorno, Chloé Najac, Olof Strandberg, Erik Stomrud, Danielle van Westen, Markus Nilsson, Itamar Ronen, Oskar Hansson

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Tau, atrophy, and domain-specific cognitive impairment in typical Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Nicola SpotornoClinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Lund 22184, Sweden.ORCID https://orcid.org/0000-0001-5404-8788
Chloé NajacDepartment of Radiology, C.J. Gorter MRI Center, Leiden University Medical Center, Leiden 2333, The Netherlands.ORCID https://orcid.org/0000-0002-7804-2281
Olof StrandbergClinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Lund 22184, Sweden.
Erik StomrudClinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Lund 22184, Sweden.
Danielle van WestenImage and Function, Skane University Hospital, Lund 22185, Sweden.ORCID https://orcid.org/0000-0001-8649-9874
Markus NilssonDiagnostic Radiology, Institution for Clinical Sciences, Lund University, Lund 22185, Sweden.
Itamar RonenClinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer BN1 9RR, UK.ORCID https://orcid.org/0000-0002-6872-4895
Oskar HanssonClinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Lund 22184, Sweden.ORCID https://orcid.org/0000-0001-8467-7286
Lund University · SEBrighton and Sussex Medical School · GBLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Alzheimer's disease, reconfiguration and deterioration of tissue microstructure occur before substantial degeneration become evident. We explored the diffusion properties of both water, a ubiquitous marker measured by diffusion MRI, and

Indexed as

Alzheimer’s diseaseastrocytesdiffusion-weighted magnetic resonance spectroscopyN-acetyl-aspartatetau

Identifiers

PMID38370447
PMCPMC10873577
OpenAlexW4391463647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.