Evidence map›Paper›PMID 38369907›Full record

ArticleJournal of intellectual disability research : JIDR2024

Hospitalisation and mortality among privately insured individuals with COVID-19 in the United States: The role of intellectual disabilities and Neurogenetic disorders.

A Davis, N Copeland-Linder, K Phuong, H Belcher, K van Eck

Abstract read
In one paragraph

Article in Journal of intellectual disability research : JIDR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

A DavisDisability Health Research Center, Johns Hopkins University School of Nursing, Baltimore, MD, USA.ORCID 0000-0002-5448-9775
N Copeland-LinderPsychology Department, Notre Dame of Maryland University, Baltimore, MD, USA.
K PhuongRenaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA.
H BelcherDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
K van EckOffice for Health, Equity, Inclusion, and Diversity, Kennedy Krieger Institute, Baltimore, MD, USA.

Funding

Interdisciplinary Research Training in Trauma and Violence (IRTTV)T32HD094687 · NICHD · JOHNS HOPKINS UNIVERSITY · PI BELCHER, HAROLYN MILLICENT EDITH, CAMPBELL, JACQUELYN CUTLER · 2018 to 2022
$1.9M
Interdisciplinary Research Training in Trauma and Violence program at Johns Hopkins School of Nursing T32HD094687-04Kennedy Krieger InstituteMaternal and Child Health-Leadership Education Advocacy Research Network (MCH-LEARN) program at Kennedy Krieger InstituteNICHD NIH HHS T32 HD094687OMHHE CDC HHS R18 MN000004
6 · The paper itself

Abstract

backgroundIndividuals with intellectual disabilities (IDs) and neurogenetic conditions (IDNDs) are at greater risk for comorbidities that may increase adverse outcomes for this population when they have coronavirus disease 2019 (COVID-19). The study aims are to examine the population-level odds of hospitalisation and mortality of privately insured individuals with COVID-19 with and without IDNDs IDs, controlling for sociodemographics and comorbid health conditions.

methodsThis is a retrospective, cross-sectional study of 1174 individuals with IDs and neurogenetic conditions within a population of 752 237 de-identified, privately insured, US patients diagnosed with COVID-19 between February 2020 and September 2020. Odds of hospitalisation and mortality among COVID-19 patients with IDNDs adjusted for demographic characteristics, Health Resources and Services Administration region, states with Affordable Care Act and number of comorbid health conditions were analysed.

resultsPatients with IDNDs overall had higher rates of COVID-19 hospitalisation than those without IDNDs (35.01% vs. 12.65%, P < .0001) and had higher rates of COVID-19 mortality than those without IDNDs (4.94% vs. .88%, P < .0001). Adjusting for sociodemographic factors only, the odds of being hospitalised for COVID-19 associated with IDNDs was 4.05 [95% confidence interval (CI) 3.56-4.61]. Adjusting for sociodemographic factors and comorbidity count, the odds of hospitalisation for COVID-19 associated with IDNDs was 1.42 (95% CI 1.25-1.61). The odds of mortality from COVID-19 for individuals with IDNDs adjusted for sociodemographic factors only was 4.65 (95% CI 3.47-6.24). The odds of mortality from COVID-19 for patients with IDNDs adjusted for sociodemographic factors and comorbidity count was 2.70 (95% CI 2.03-3.60). A major finding of the study was that even when considering the different demographic structure and generally higher disease burden of patients with IDNDs, having a IDND was an independent risk factor for increased hospitalisation and mortality compared with patients without IDNDs.

conclusionsIndividuals with IDNDs had significantly higher odds of hospitalisation and mortality after adjusting for sociodemographics. Results remained significant with a slight attenuation after adjusting for sociodemographics and comorbidities. Adjustments for comorbidity count demonstrated a dose-response increase in odds of both hospitalisation and mortality, illustrating the cumulative effect of health concerns on COVID-19 outcomes. Together, findings highlight that individuals with IDNDs experience vulnerability for negative COVID-19 health outcomes with implications for access to comprehensive healthcare.

Indexed as

ComorbidityCOVID-19HospitalizationIntellectual DisabilityAdolescentAdultAgedChildChild, PreschoolCross-Sectional StudiesFemaleHumansInsurance, HealthMaleMiddle AgedRetrospective StudiesCOVID‐19 health outcomeshealthcare servicesHealth inequitiesIntellectual disabilitymortalityNeurogenetic Disorder

Identifiers

PMID38369907
PMCPMC11809292

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.