Evidence map›Paper›PMID 38369682›Full record

ArticleInternational journal of legal medicine2024

Development of a novel five dye insertion/deletion (INDEL) panel for ancestry determination.

Lucio L Avellaneda, Damani T Johnson, Ryan M Gutierrez, Lindsey Thompson, Sarah A Sturm, Kelly A Sage, Rachel M Houston, Bobby L LaRue

Abstract read
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In one paragraph

Article in International journal of legal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lucio L AvellanedaDepartment of Forensic Science, Sam Houston State University, 1003 Bowers Blvd., Huntsville, TX, 77340, USA. lxa040@shsu.edu.ORCID http://orcid.org/0000-0002-3613-0291
Damani T JohnsonDepartment of Forensic Science, Sam Houston State University, 1003 Bowers Blvd., Huntsville, TX, 77340, USA.ORCID http://orcid.org/0009-0007-0900-2351
Ryan M GutierrezDepartment of Forensic Science, Sam Houston State University, 1003 Bowers Blvd., Huntsville, TX, 77340, USA.ORCID http://orcid.org/0000-0002-7471-7157
Lindsey ThompsonInstitute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Sarah A SturmInstitute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Kelly A SageInstitute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Rachel M HoustonDepartment of Forensic Science, Sam Houston State University, 1003 Bowers Blvd., Huntsville, TX, 77340, USA.ORCID http://orcid.org/0000-0001-9833-6837
Bobby L LaRueDepartment of Forensic Science, Sam Houston State University, 1003 Bowers Blvd., Huntsville, TX, 77340, USA.ORCID http://orcid.org/0000-0002-8279-9578

Funding

National Institute of Justice 2013-DN-BX-K036
6 · The paper itself

Abstract

The use of genetic markers, specifically Short Tandem Repeats (STRs), has been a valuable tool for identifying persons of interest. However, the ability to analyze additional markers including Single Nucleotide Polymorphisms (SNPs) and Insertion/Deletion (INDELs) polymorphisms allows laboratories to explore other investigative leads. INDELs were chosen in this study because large panels can be differentiated by size, allowing them to be genotyped by capillary electrophoresis. Moreover, these markers do not produce stutter and are smaller in size than STRs, facilitating the recovery of genetic information from degraded samples. The INDEL Ancestry Informative Markers (AIMs) in this study were selected from the 1000 Genomes Project based on a fixation index (F

Indexed as

Electrophoresis, CapillaryINDEL MutationPrincipal Component AnalysisRacial GroupsBayes TheoremDNA FingerprintingGene FrequencyGenetic MarkersGenetics, PopulationGenotypeHumansMicrosatellite RepeatsUnited StatesGenetic MarkersAncestry informative markersBi-allelicCapillary electrophoresisInsertion deletion polymorphisms

Identifiers

PMID38369682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.