Evidence map›Paper›PMID 38369626›Full record

ArticleScientific reports2024

Impact of nonspecific allograft biopsy findings in symptomatic kidney transplant recipients.

Bon Jin Koo, Hyuk Huh, Byung Min Ye, Yunmi Kim, Byung Hyun Choi, Hyun Jeong Lee, Mi Seon Kang, Dong Won Lee, Soo Bong Lee, Yeong Hoon Kim and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Bon Jin KooDivision of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Hyuk HuhDepartment of Internal Medicine-Nephrology, Inje University Busan Paik Hospital, Busan, South Korea.
Byung Min YeDivision of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Yunmi KimDepartment of Internal Medicine-Nephrology, Inje University Busan Paik Hospital, Busan, South Korea.
Byung Hyun ChoiResearch Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Hyun Jeong LeeDepartment of Pathology, Pusan National University School of Medicine, Yangsan, South Korea.
Mi Seon KangDepartment of Pathology, Inje University Busan Paik Hospital, Busan, South Korea.
Dong Won LeeDivision of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Soo Bong LeeDivision of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Yeong Hoon KimDepartment of Internal Medicine-Nephrology, Inje University Busan Paik Hospital, Busan, South Korea.
Il Young KimDivision of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Taehee KimDepartment of Internal Medicine-Nephrology, Inje University Busan Paik Hospital, Busan, South Korea.
Seo Rin KimDivision of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, South Korea. kim.seorin@hotmail.com.
Inje University Busan Paik Hospital · KRPusan National University · KRPusan National University Yangsan Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A for-cause biopsy is performed to diagnose the cause of allograft dysfunction in kidney transplantation. We occasionally encounter ambiguous biopsy results in symptomatic kidney transplant recipients. Yet, the allograft survival outcome in symptomatic recipients with nonspecific allograft biopsy findings remains unclear. The purpose of this study was to analyze the impact of nonspecific for-cause biopsy findings in symptomatic kidney transplant recipients. We retrospectively collected records from 773 kidney transplant recipients between January 2008 and October 2021. The characteristics of transplant recipients with nonspecific findings in the first for-cause biopsy were analyzed. Nonspecific allograft biopsy findings were defined as other biopsy findings excluding rejection, borderline rejection, calcineurin inhibitor toxicity, infection, glomerulonephritis, and diabetic nephropathy. The graft outcome was compared between recipients who had never undergone a for-cause biopsy and those who had a first for-cause biopsy with nonspecific findings. The graft survival in recipients with nonspecific for-cause biopsy findings was comparable to that in recipients who did not require the for-cause biopsy before and after propensity score matching. Even in symptomatic kidney transplant recipients, nonspecific allograft biopsy findings might not be a poor prognostic factor for allograft survival compared to recipients who did not require the for-cause biopsy.

Indexed as

Kidney TransplantationAllograftsBiopsyGraft RejectionGraft SurvivalHumansKidneyRetrospective StudiesTransplant RecipientsAllograftFor-cause biopsyIndication biopsyKidney transplantation

Identifiers

PMID38369626
PMCPMC10874932
OpenAlexW4391917685

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.