Evidence map›Paper›PMID 38369239›Full record

ArticleThe Journal of pediatrics2024

Racial and Ethnic Inequities in Therapeutic Hypothermia and Neonatal Hypoxic-Ischemic Encephalopathy: A Retrospective Cohort Study.

Carolyn Fall, Rebecca J Baer, Laura Jelliffe-Pawlowski, Nana Matoba, Henry C Lee, Christina D Chambers, Gretchen Bandoli

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
11.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Carolyn FallRady Children's Hospital of San Diego, University of California, San Diego, San Diego, CA.
Rebecca J BaerDivision of Pediatrics, University of California San Diego, San Diego, CA; Division of Epidemiology, Biostatistics, University of California San Francisco, San Francisco, CA.
Laura Jelliffe-PawlowskiDivision of Epidemiology, Biostatistics, University of California San Francisco, San Francisco, CA.
Nana MatobaRady Children's Hospital of San Diego, University of California, San Diego, San Diego, CA.
Henry C LeeRady Children's Hospital of San Diego, University of California, San Diego, San Diego, CA.
Christina D ChambersRady Children's Hospital of San Diego, University of California, San Diego, San Diego, CA.
Gretchen BandoliRady Children's Hospital of San Diego, University of California, San Diego, San Diego, CA.
University of California San Diego · USUniversity of California, San Francisco · US

Funding

Applying Machine Learning in the Prediction and Identification of Children Affected by Prenatal Alcohol ExposureK01AA027811 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BANDOLI, GRETCHEN E. · 2019 to 2023
$865k
NIAAA NIH HHS K01 AA027811
6 · The paper itself

Abstract

objectiveTo investigate racial inequities in the use of therapeutic hypothermia (TH) and outcomes in infants with hypoxic-ischemic encephalopathy (HIE). STUDY

designWe queried an administrative birth cohort of mother-baby pairs in California from 2010 through 2019 using International Classification of Diseases codes to evaluate the association between race and ethnicity and the application of TH in infants with HIE. We identified 4779 infants with HIE. Log-linear regression was used to calculate risk ratios (RR) for TH, adjusting for hospital transfer, rural location, gestational age between 35 and 37 weeks, and HIE severity. Risk of adverse infant outcome was calculated by race and ethnicity and stratified by TH.

resultsFrom our identified cohort, 1338 (28.0%) neonates underwent TH. White infants were used as the reference sample, and 410 (28.4%) received TH. Black infants were significantly less likely to receive TH with 74 (20.0%) with an adjusted risk ratio (aRR) of 0.7 (95% CI 0.5-0.9). Black infants with any HIE who did not receive TH were more likely to have a hospital readmission (aRR 1.36, 95% CI 1.10-1.68) and a tracheostomy (aRR 3.07, 95% CI 1.19-7.97). Black infants with moderate/severe HIE who did not receive TH were more likely to have cerebral palsy (aRR 2.72, 95% CI 1.07-6.91).

conclusionsIn this study cohort, Black infants with HIE were significantly less likely to receive TH. Black infants also had significantly increased risk of some adverse outcomes of HIE. Possible reasons for this inequity include systemic barriers to care and systemic bias.

Indexed as

Healthcare DisparitiesHypothermia, InducedHypoxia-Ischemia, BrainBlack or African AmericanCaliforniaEthnicityFemaleHumansInfant, NewbornMaleRetrospective StudiesWhitebiasstructural racism

Identifiers

PMID38369239
PMCPMC11096019
OpenAlexW4391888008

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.