Evidence map›Paper›PMID 38368385›Full record

ArticleParticle and fibre toxicology2024

Effective density of inhaled environmental and engineered nanoparticles and its impact on the lung deposition and dosimetry.

Denisa Lizonova, Amogh Nagarkar, Philip Demokritou, Georgios A Kelesidis

Open access · goldAbstract read
In one paragraph

Article in Particle and fibre toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. SiOScientific reports · 2025
    Article
  6. Nanotoxicology: developments and new insights.Nanomedicine (London, England) · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Denisa LizonovaNanoscience and Advanced Materials Center (NAMC), Environmental and Occupational Health Science Institute, School of Public Health, Rutgers, The State University of New Jersey, 170 Frelinghuysen Road, Piscataway, NJ, 08854, USA.
Amogh NagarkarParticle Technology Laboratory, Department of Mechanical and Process Engineering, Institute of Process Engineering, ETH Zürich, Sonneggstrasse 3, 8092, Zurich, Switzerland.
Philip DemokritouNanoscience and Advanced Materials Center (NAMC), Environmental and Occupational Health Science Institute, School of Public Health, Rutgers, The State University of New Jersey, 170 Frelinghuysen Road, Piscataway, NJ, 08854, USA.
Georgios A KelesidisNanoscience and Advanced Materials Center (NAMC), Environmental and Occupational Health Science Institute, School of Public Health, Rutgers, The State University of New Jersey, 170 Frelinghuysen Road, Piscataway, NJ, 08854, USA. georgios.kelesidis@rutgers.edu.
Rutgers, The State University of New Jersey · USETH Zurich · CH

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4M
DNA Protein Cross-Links:Cellular Effects and Repair MechanismsR01ES023350 · NIEHS · UNIVERSITY OF MINNESOTA · PI CAMPBELL, COLIN R, TRETYAKOVA, NATALIA Y · 2014 to 2023
$5.0M
EPHEDRA: Enhanced PHthisic by Environmental Disruptors of Resolution AgonistsR56ES033250 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI LEVY, BRUCE D, SERHAN, CHARLES NICHOLAS · 2022 to 2022
$511k
NIEHS NIH HHS P30 ES005022NIEHS NIH HHS R01 ES023350NIEHS NIH HHS R56 ES033250
6 · The paper itself

Abstract

backgroundAirborne environmental and engineered nanoparticles (NPs) are inhaled and deposited in the respiratory system. The inhaled dose of such NPs and their deposition location in the lung determines their impact on health. When calculating NP deposition using particle inhalation models, a common approach is to use the bulk material density, ρ

resultsHere, the deposition of various environmental NPs (aircraft and diesel black carbon, wood smoke) and engineered NPs (silica, zirconia) in the respiratory system of humans and mice is calculated using the Multiple-Path Particle Dosimetry model accounting for their realistic structure and effective density. This is done by measuring the NP ρ

conclusionsThe doses of inhaled NPs are overestimated by inhalation particle deposition models when the ρ

Indexed as

Inhalation ExposureNanoparticlesAnimalsCarbonHumansLungMiceParticle SizeSootCarbonSootAir pollutionBlack carbonEffective densityEngineered nanoparticlesInhalationPulmonary depositionWood smoke

Identifiers

PMID38368385
PMCPMC10874077
OpenAlexW4391897783

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.