Evidence map›Paper›PMID 38368295›Full record

ArticleMikrochimica acta2024

Modified exfoliated graphene functionalized with carboxylic acid-group and thionine on a screen-printed carbon electrode as a platform for an electrochemical enzyme immunosensor.

Jing Wang, Liang Zhang, Guanrong Yan, Linfeng Cheng, Fanglin Zhang, Jialin Wu, Yingfeng Lei, Qunxing An, Honglan Qi, Chengxiao Zhang and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Tailored Viral-like Particles as Drivers of Medical Breakthroughs.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jing WangKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, China.
Liang ZhangDepartment of Microbiology, Faculty of Preclinical Medicine, Air Force Medical University, Xi'an, 710032, Shaanxi, China.
Guanrong YanKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, China.
Linfeng ChengDepartment of Microbiology, Faculty of Preclinical Medicine, Air Force Medical University, Xi'an, 710032, Shaanxi, China.
Fanglin ZhangDepartment of Microbiology, Faculty of Preclinical Medicine, Air Force Medical University, Xi'an, 710032, Shaanxi, China. flzhang@fmmu.edu.cn.
Jialin WuKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, China.
Yingfeng LeiDepartment of Microbiology, Faculty of Preclinical Medicine, Air Force Medical University, Xi'an, 710032, Shaanxi, China.
Qunxing AnDepartment of Transfusion Medicine, The First Affiliated Hospital of Air Force Medical University, Xi'an, 710032, Shaanxi, China. bestar01@163.com.
Honglan QiKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, China.
Chengxiao ZhangKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, China.
Qiang GaoKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, China. gaoqiang@snnu.edu.cn.ORCID http://orcid.org/0000-0002-0775-3414
Shaanxi Normal University · CNAir Force Medical University · CNAir Force Engineering University · CNXi'an Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An enzyme immunoassay was developed based on the coulometric measurement of immunoglobulin M (IgM) against Hantaan viruses (HTNV) by using virus-like particles (VLPs) as recognition molecules. The surface functionalization of screen-printed carbon electrodes (SPCEs) was achieved through paste-exfoliated graphene that was modified with a COOH group and a thionine mediator through supramolecular-covalent scaffolds, on SPCEs by using the binder contained in the ink. After the covalent immobilization of the antibody, the sensor was used for the sandwich enzyme immunoassay of IgM against HTNV. By using HTNV VLPs as the second recognization molecules, the resulting sensor efficiently monitored the reaction of IgM against HTNV and anti-IgM antibody with high specificity. By attaching HTNV nucleocapsid protein antibody conjugate with horseradish peroxidase (HRP) onto VLPs, the signal response of the assay was derived from the coulometric measurement of H

Indexed as

Biosensing TechniquesGraphitePhenothiazinesCarbonElectrodesHydrogen PeroxideImmunoassayImmunoglobulin MCarbonGraphiteHydrogen PeroxideImmunoglobulin MPhenothiazinesthionineCoulometryExfoliated grapheneFunctionalizationImmunoassayScreen-printed carbon electrodeVirus-like particle

Identifiers

PMID38368295
OpenAlexW4391895759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.