Evidence map›Paper›PMID 38367966›Full record

ArticleBMJ open2024

Nudging towards COVID-19 and influenza vaccination uptake in medically at-risk children: EPIC study protocol of randomised controlled trials in Australian paediatric outpatient clinics.

Bing Wang, Prabha Andraweera, Margaret Danchin, Christopher C Blyth, Ivo Vlaev, Jason Ong, Jodie M Dodd, Jennifer Couper, Thomas R Sullivan, Jonathan Karnon and 10 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05613751 (Enhancing Protection Against Influenza and COVID-19 for Pregnant Women and Medically at Risk Children), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05613751 naunknown statusnot on this map

Enhancing Protection Against Influenza and COVID-19 for Pregnant Women and Medically at Risk Children (EPIC Study)

TypeinterventionalSponsorUniversity of AdelaideRan2022 to 2024Enrolled1,038ConditionsInfluenza, COVID-19ArmsNudge
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 12 institutions in 4 countries.

Bing WangVaccinology and Immunology Research Trials Unit, Women's and Children's Hospital, Adelaide, South Australia, Australia.
Prabha AndraweeraVaccinology and Immunology Research Trials Unit, Women's and Children's Hospital, Adelaide, South Australia, Australia.
Margaret DanchinMurdoch Childrens Research Institute, Melbourne, Victoria, Australia.
Christopher C BlythWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute and School of Medicine, University of Western Australia, Perth, Western Australia, Australia.
Ivo VlaevSchool of Business, Warwick University, Warwick, UK.ORCID 0000-0002-3218-0144
Jason OngMelbourne Sexual Health Clinic & LSHTM, Monash University, Carlton, Victoria, Australia.
Jodie M DoddRobinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0002-6363-4874
Jennifer CouperRobinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.
Thomas R SullivanSouth Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.ORCID 0000-0002-6930-5406
Jonathan KarnonDiscipline of Public Health, Flinders University, Adelaide, South Australia, Australia.
Nicola SpurrierSA Health, South Australian Government, Adelaide, South Australia, Australia.
Michael CusackSA Health, South Australian Government, Adelaide, South Australia, Australia.
Dylan MordauntDiscipline of Paediatrics, Flinders University, Adelaide, South Australia, Australia.
Dimi SimatosDiscipline of Paediatrics Lyell McEwin Hospital, Elizabeth Vale, South Australia, Australia.
Gustaaf DekkerRobinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.
Samantha CarlsonWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute and School of Medicine, University of Western Australia, Perth, Western Australia, Australia.
Jane TuckermanMurdoch Childrens Research Institute, Melbourne, Victoria, Australia.ORCID 0000-0001-6938-1751
Nicholas WoodDiscipline of Paediatrics, University of Sydney, Sydney, New South Wales, Australia.
Lisa J WhopDiscipline of Public Health, Australian National University, Canberra, ACT, Australia.
Helen MarshallVaccinology and Immunology Research Trials Unit, Women's and Children's Hospital, Adelaide, South Australia, Australia helen.marshall@adelaide.edu.au.ORCID 0000-0003-2521-5166
Women's and Children's Hospital · AUFlinders University · AULyell McEwin Hospital · AUThe Kids Research Institute Australia · AUAustralian National University · AUAustralian Regenerative Medicine Institute · AUGovernment of South Australia · AURoyal Children's Hospital · AUSouth Australian Health and Medical Research Institute · AUThe University of Melbourne · AUThe University of Sydney · AUUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChildren with chronic medical diseases are at an unacceptable risk of hospitalisation and death from influenza and SARS-CoV-2 infections. Over the past two decades, behavioural scientists have learnt how to design non-coercive 'nudge' interventions to encourage positive health behaviours. Our study aims to evaluate the impact of multicomponent nudge interventions on the uptake of COVID-19 and influenza vaccines in medically at-risk children. METHODS AND ANALYSES: Two separate randomised controlled trials (RCTs), each with 1038 children, will enrol a total of approximately 2076 children with chronic medical conditions who are attending tertiary hospitals in South Australia, Western Australia and Victoria. Participants will be randomly assigned (1:1) to the standard care or intervention group. The nudge intervention in each RCT will consist of three text message reminders with four behavioural nudges including (1) social norm messages, (2) different messengers through links to short educational videos from a paediatrician, medically at-risk child and parent and nurse, (3) a pledge to have their child or themselves vaccinated and (4) information salience through links to the current guidelines and vaccine safety information. The primary outcome is the proportion of medically at-risk children who receive at least one dose of vaccine within 3 months of randomisation. Logistic regression analysis will be performed to determine the effect of the intervention on the probability of vaccination uptake. ETHICS AND DISSEMINATION: The protocol and study documents have been reviewed and approved by the Women's and Children's Health Network Human Research Ethics Committee (HREC/22/WCHN/2022/00082). The results will be published via peer-reviewed journals and presented at scientific meetings and public forums. TRIAL REGISTRATION NUMBER: NCT05613751.

Indexed as

COVID-19Influenza, HumanInfluenza VaccinesRandomized Controlled Trials as TopicSARS-CoV-2AdolescentAmbulatory Care FacilitiesAustraliaChildChild, PreschoolChronic DiseaseCOVID-19 VaccinesFemaleHealth BehaviorHumansMaleCOVID-19 VaccinesInfluenza VaccinesCOVID-19INFECTIOUS DISEASESPrimary PreventionPublic health

Identifiers

PMID38367966
PMCPMC10875525
OpenAlexW4391899737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.