ArticleEndocrine2024
Association between phase angle and diabetic peripheral neuropathy in Type 2 diabetes patients.
Article in Endocrine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Relationship between low phase angle and impaired healing of diabetic foot ulcer: a retrospective cohort study.Nutrition & metabolism · 2026Article
- Phase angle as an early-warning indicator of glycaemic control in adults with type 1 diabetes mellitus: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Phase Angle Evaluated by a Bioimpedance Analysis Is Closely Related to Diabetic Nephropathy and Peripheral Neuropathy in Patients with Type 2 Diabetes.JMA journal · 2025Article
- Stronger associations of the phase angle than the TyG index with micro- and macrovascular complications in patients with type 2 diabetes.Lipids in health and disease · 2025Article
- Identification of phase angle and Triglyceride-Glucose index as biomarkers for prediction and management of diabetic foot disease.Metabolism open · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetic peripheral neuropathy (DPN), the very prevalent microvascular complication of type 2 diabetes mellitus (T2DM), severely threatens the quality of life of diabetic patients. Thus, prevention of DPN is extremely important for public health, and the identification of potential biomarkers may help with early prevention. Our work determined the association between phase angles (PhAs) and the risk of DPN in T2DM patients. MATERIALS AND
methodsThis cross-sectional study recruited 697 T2DM patients from the Third Affiliated Hospital of Soochow University. All patients were divided into the non-diabetic peripheral neuropathy group and diabetic peripheral neuropathy group, and the DPN group was further divided into low, medium, and high diabetic foot ulcer risk groups according to vibration perception threshold results. Using univariate and multivariate logistic regression analyses continuously, the relationship between PhAs (arms, legs, trunk, and whole body) and the risk of DPN were evaluated. Further analysis was conducted on different subgroups of the study population.
resultsAfter adjusting for the potential covariates, multivariate logistic regression analyses indicated that PhAs of the arms, legs, and whole body correlated inversely with the risk of DPN. However, the PhA of the trunk had no significant correlation with DPN. According to the stratified subgroup analysis, the negative association between PhA of the whole body and the risk of DPN remained significant in the sex and BMI group except for participants with BMI ≥ 28 kg/m².
conclusionsFor the first time, PhAs were acknowledged to be independently associated with DPN. Further exploration is needed to explain the findings.
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