Evidence map›Paper›PMID 38366879›Full record

SynthesisJournal of the American Medical Informatics Association : JAMIA2024

Question answering systems for health professionals at the point of care-a systematic review.

Gregory Kell, Angus Roberts, Serge Umansky, Linglong Qian, Davide Ferrari, Frank Soboczenski, Byron C Wallace, Nikhil Patel, Iain J Marshall

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Medical Informatics Association : JAMIA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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  9. Redefining digital health interfaces with large language models.Frontiers in artificial intelligence · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Gregory KellDepartment of Population Health Sciences, King's College London, London, Greater London, SE1 1UL, United Kingdom.
Angus RobertsDepartment of Biostatistics and Health Informatics, King's College London, London, Greater London, SE5 8AB, United Kingdom.
Serge UmanskyMetadvice Ltd, London, Greater London, SW1Y 5JG, United Kingdom.
Linglong QianDepartment of Biostatistics and Health Informatics, King's College London, London, Greater London, SE5 8AB, United Kingdom.
Davide FerrariDepartment of Population Health Sciences, King's College London, London, Greater London, SE1 1UL, United Kingdom.
Frank SoboczenskiDepartment of Population Health Sciences, King's College London, London, Greater London, SE1 1UL, United Kingdom.
Byron C WallaceKhoury College of Computer Sciences, Northeastern University, Boston, MA 02115, United States.
Nikhil PatelDepartment of Population Health Sciences, King's College London, London, Greater London, SE1 1UL, United Kingdom.
Iain J MarshallDepartment of Population Health Sciences, King's College London, London, Greater London, SE1 1UL, United Kingdom.ORCID 0000-0003-2594-2654
King's College London · GBNortheastern University · US

Funding

Semi-Automating Data Extraction for Systematic ReviewsR01LM012086 · NLM · UNIVERSITY OF TEXAS AT AUSTIN · PI MARSHALL, IAIN, WALLACE, BYRON CASEY · 2015 to 2022
$2.4M
NIH HHSNLM NIH HHS R01 LM012086NLM NIH HHS R01-LM012086-01A1
6 · The paper itself

Abstract

objectivesQuestion answering (QA) systems have the potential to improve the quality of clinical care by providing health professionals with the latest and most relevant evidence. However, QA systems have not been widely adopted. This systematic review aims to characterize current medical QA systems, assess their suitability for healthcare, and identify areas of improvement. MATERIALS AND

methodsWe searched PubMed, IEEE Xplore, ACM Digital Library, ACL Anthology, and forward and backward citations on February 7, 2023. We included peer-reviewed journal and conference papers describing the design and evaluation of biomedical QA systems. Two reviewers screened titles, abstracts, and full-text articles. We conducted a narrative synthesis and risk of bias assessment for each study. We assessed the utility of biomedical QA systems.

resultsWe included 79 studies and identified themes, including question realism, answer reliability, answer utility, clinical specialism, systems, usability, and evaluation methods. Clinicians' questions used to train and evaluate QA systems were restricted to certain sources, types and complexity levels. No system communicated confidence levels in the answers or sources. Many studies suffered from high risks of bias and applicability concerns. Only 8 studies completely satisfied any criterion for clinical utility, and only 7 reported user evaluations. Most systems were built with limited input from clinicians. DISCUSSION: While machine learning methods have led to increased accuracy, most studies imperfectly reflected real-world healthcare information needs. Key research priorities include developing more realistic healthcare QA datasets and considering the reliability of answer sources, rather than merely focusing on accuracy.

Indexed as

Point-of-Care SystemsHealth PersonnelHumansQuality Assurance, Health Careartificial intelligenceclinical decision supportevidence-based medicinenatural language processingquestion answering

Identifiers

PMID38366879
PMCPMC10990539
OpenAlexW4391897343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.