Evidence map›Paper›PMID 38366869›Full record

ArticleJournal of diabetes investigation2024

Interactive calculator to estimate insulin sensitivity in type 1 diabetes.

Andrzej S Januszewski, Pawel Niedzwiecki, Nirupa Sachithanandan, Glenn M Ward, David N O'Neal, Dorota A Zozulinska-Ziolkiewicz, Aleksandra A Uruska, Alicia J Jenkins

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Andrzej S JanuszewskiNHMRC Clinical Trials Centre, University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0003-0995-4524
Pawel NiedzwieckiDepartment of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Nirupa SachithanandanDepartment of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
Glenn M WardDepartment of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
David N O'NealDepartment of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
Dorota A Zozulinska-Ziolkiewicz *Department of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Aleksandra A Uruska *Department of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Alicia J Jenkins *NHMRC Clinical Trials Centre, University of Sydney, Sydney, New South Wales, Australia.
Poznan University of Medical Sciences · PLThe University of Melbourne · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gold standard for measuring insulin sensitivity (IS) is the hyperinsulinemic-euglycemic clamp, a time, costly, and labor-intensive research tool. A low insulin sensitivity is associated with a complication-risk in type 1 diabetes. Various formulae using clinical data have been developed and correlated with measured IS in type 1 diabetes. We consolidated multiple formulae into an online calculator (bit.ly/estimated-GDR), enabling comparison of IS and its probability of IS <4.45 mg/kg/min (low) or >6.50 mg/kg/min (high), as measured in a validation set of clamps in 104 adults with type 1 diabetes. Insulin sensitivity calculations using different formulae varied significantly, with correlations (R

Indexed as

Diabetes Mellitus, Type 1Glucose Clamp TechniqueInsulin ResistanceAdultBlood GlucoseFemaleHumansInsulinMaleMiddle AgedBlood GlucoseInsulinInsulin sensitivityOnline calculatorType 1 diabetes

Identifiers

PMID38366869
PMCPMC11060155
OpenAlexW4391897137

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.