Evidence map›Paper›PMID 38366326›Full record

ArticleJournal of the American Heart Association2024

Hypertension in Pregnancy Among Immigrant and Swedish Women: A Cohort Study of All Pregnant Women in Sweden.

Per Wändell, Casey Crump, Xinjun Li, Nouha Saleh Stattin, Axel C Carlsson, Jan Sundquist, Kristina Sundquist

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Preeclampsia, the placenta, ethnicity, and social determinants of health.Acta obstetricia et gynecologica Scandinavica · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Per WändellDivision of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society Karolinska Institutet Huddinge Sweden.ORCID 0000-0001-5169-2965
Casey CrumpDepartment of Family and Community Medicine and of Epidemiology, Human Genetics and Environmental Sciences The University of Texas Health Science Center Houston TX.ORCID 0000-0002-2990-1166
Xinjun LiCenter for Primary Health Care Research Lund University Malmö Sweden.ORCID 0000-0002-5559-4657
Nouha Saleh StattinDivision of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society Karolinska Institutet Huddinge Sweden.ORCID 0000-0002-3211-1376
Axel C CarlssonDivision of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society Karolinska Institutet Huddinge Sweden.ORCID 0000-0001-6113-0472
Jan SundquistDepartment of Family and Community Medicine and of Epidemiology, Human Genetics and Environmental Sciences The University of Texas Health Science Center Houston TX.ORCID 0000-0001-7228-5015
Kristina SundquistDepartment of Family and Community Medicine and of Epidemiology, Human Genetics and Environmental Sciences The University of Texas Health Science Center Houston TX.ORCID 0000-0001-8031-279X
Karolinska Institutet · SEShimane University · JPLund University · SEThe University of Texas Health Science Center at Houston · US

Funding

Preterm birth and long-term risk of cardiovascular disease in mothers and offspringR01HL139536 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CRUMP, CASEY, SUNDQUIST, KRISTINA · 2018 to 2025
$5.3M
NHLBI NIH HHS R01 HL139536
6 · The paper itself

Abstract

backgroundLittle is known about risks of hypertensive disorders of pregnancy in both first- and second-generation immigrant women in Europe and other Western countries; such knowledge may help elucidate the influence of genetic versus social factors on such risks. We aimed to study both first- and second-generation immigrant women for the presence of all types of hypertension (preexisting hypertension, gestational hypertension, preeclampsia, and eclampsia) during pregnancy. METHODS AND

resultsA cohort study was conducted using data derived from the Swedish National Birth Register, the National Patient Register, and the Total Population Register. We used Cox regression analysis to compute hazard ratios (HRs) and 99% CIs while adjusting for sociodemographic factors and comorbidities. The first-generation study included a total of 1 084 212 deliveries and 68 311 hypertension cases, and the second-generation study included 989 986 deliveries and 67 505 hypertension cases. The fully adjusted HR (with 99% CI) for hypertension in pregnancy among first-generation immigrant women was 0.69 (0.66-0.72), and among second-generation immigrant women, it was 0.88 (0.86-0.91), compared with Swedish-born women with 2 Swedish-born parents. Women born in Finland or with parent(s) from Finland had higher risks, with fully adjusted HRs (99% CIs) of 1.30 (1.18-1.43) and 1.12 (1.07-1.17), respectively.

conclusionsBoth first- and second-generation immigrant women had overall lower risks of hypertension in pregnancy compared with other Swedish women. However, the risk reduction was less pronounced in second-generation compared with first-generation immigrant women, suggesting that environmental factors in Sweden may have an important influence on risk of hypertension during pregnancy.

Indexed as

Emigrants and ImmigrantsHypertension, Pregnancy-InducedCohort StudiesFemaleHumansParturitionPregnancyPregnant PeopleRisk FactorsSwedendiabetesgestational diabeteshypertensionimmigrant womensocioeconomic factors

Identifiers

PMID38366326
PMCPMC10944082
OpenAlexW4391914315

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.