Evidence map›Paper›PMID 38366157›Full record

ReviewEuropean journal of cardiovascular nursing2024

Hitting the (bio)mark Part 2: analysing, interpreting, and reporting biomarker data in cardiovascular research.

Quin E Denfeld, Bo Daelman, Brittany Butts

Abstract readReview
In one paragraph

Review in European journal of cardiovascular nursing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Quin E DenfeldSchool of Nursing and Knight Cardiovascular Institute, Oregon Health & Science University, 3455 S.W. U.S. Veterans Hospital Road | Mail code: SN-ORD, Portland, OR 97239-2941, USA.ORCID 0000-0001-7568-9568
Bo DaelmanKU Leuven Department of Public Health and Primary Care, KU Leuven-University of Leuven, Leuven, Belgium.ORCID 0000-0002-5135-5384
Brittany ButtsNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.ORCID 0000-0002-4862-7086

Funding

Scholars in Women's Health Research Across the LifespanK12HD043488 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI MYATT, LESLIE · 2002 to 2023
$10.4M
Biological and Physiological Mechanisms of Symptom Clusters in Heart Failure (BIOMES-HF)R01NR019054 · NINR · OREGON HEALTH & SCIENCE UNIVERSITY · PI DENFELD, QUIN ELEANOR · 2021 to 2024
$2.3M
Midlife Vascular Risk Factors for Alzheimer's Disease in Persons with HFpEFK23AG076977 · NIA · EMORY UNIVERSITY · PI Brittany Butts · 2023 to 2026
$771k
Eunice Kennedy Shriver National Institute of Child Health & Human DevelopmentKU Leuven-University of LeuvenNIA NIH HHS K23 AG076977NICHD NIH HHS K12 HD043488NIH HHS R01NR019054NINR NIH HHS R01 NR019054Office of Research on Women's HealthResearch Foundation Flanders ZKE1844-01-W01
6 · The paper itself

Abstract

Incorporating biomarkers into cardiovascular studies, including nursing research, is a common approach when identifying underlying mechanisms and providing targets for intervention. However, effective utilization of biomarker data demands careful consideration. In the analysis, interpretation, and reporting phase, there are many facets to consider, including non-normality of the data, normalization procedures, and potential confounding influences of other clinical data. Furthermore, as many studies focus on patient-reported outcomes (PROs), it is important that the analysis and interpretation of biomarkers in relation to PROs is rigorous and reproducible. In this article, Part 2 of 2, we provide an overview of considerations for the analysis, interpretation, and reporting phases of biomarker studies. We also provide an example of these steps.

Indexed as

BiomarkersCardiovascular DiseasesCardiovascular NursingData Interpretation, StatisticalHumansNursing ResearchResearch DesignBiomarkersBiomarkersResearch methods

Identifiers

PMID38366157
PMCPMC11389263

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.