Evidence map›Paper›PMID 38365991›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Voice outcome in medialisation thyroplasty with and without arytenoid adduction: a prospective comparison using intraoperative voice measurements.

S D Mes, M A van der Jagt, J C Jansen, A P M Langeveld, E V Sjögren, B J Heijnen

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07579364 (Outcomes Tracking in Unilateral Vocal Fold Paralysis), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07579364 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Outcomes Tracking in Unilateral Vocal Fold Paralysis (UVFP) and Atrophy After Medialization Laryngeal Surgery

Typeobservational_patient_registrySponsorUniversity of California, San FranciscoRan2025 to 2028Enrolled500ConditionsUnilateral Vocal Cord Paralysis, Vocal Cord AtrophyArmsLaryngeal Framework Surgery
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

S D MesDepartment of Otolaryngology and Head- and Neck Surgery, Leiden University Medical Center, Albinusdreef 2, Postbus 9600, Leiden, RC, The Netherlands. s.d.mes@lumc.nl.ORCID http://orcid.org/0000-0002-9796-8434
M A van der JagtDepartment of Otolaryngology, Alrijne Hospital, Leiden, The Netherlands.
J C JansenDepartment of Otolaryngology and Head- and Neck Surgery, Leiden University Medical Center, Albinusdreef 2, Postbus 9600, Leiden, RC, The Netherlands.
A P M LangeveldDepartment of Otolaryngology and Head- and Neck Surgery, Leiden University Medical Center, Albinusdreef 2, Postbus 9600, Leiden, RC, The Netherlands.
E V SjögrenDepartment of Otolaryngology and Head- and Neck Surgery, Leiden University Medical Center, Albinusdreef 2, Postbus 9600, Leiden, RC, The Netherlands.
B J HeijnenDepartment of Otolaryngology and Head- and Neck Surgery, Leiden University Medical Center, Albinusdreef 2, Postbus 9600, Leiden, RC, The Netherlands.
Leiden University Medical Center · NLAlrijne Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeArytenoid adduction as an addition to medialisation thyroplasty is highly advocated by some surgeons in selected cases but deemed less necessary by others in patients with unilateral vocal fold paralysis. This study aims to evaluate the additional benefits on voice outcome of arytenoid adduction in patients with unilateral vocal fold paralysis undergoing medialisation thyroplasty using intra-operative voice measurements. DESIGN/

methodsA prospective study was conducted. Voice audio recordings were obtained at 4 moments; 1. direct prior to the start of surgery, 2. during surgery after medialisation thyroplasty, 3. during surgery after medialisation and arytenoid adduction, 3 months postoperative. At these same timepoints patients rated their own voice on a numeric rating scale between 0 and 10. The blinded recordings were rated by consensus in a team of experienced listeners, using the Grade of the GRBAS scale. Furthermore, the Voice Handicap Index was administered before and at 3 months after surgery.

resultsTen patients who underwent medialisation and arytenoid adduction at our tertiary referral hospital between 2021 and 2022, were included. One patient was excluded after surgery. The intraoperative measurements showed a Grade score of 1.4 preoperatively, improving to 1.2 after medialisation, 1.2 after medialisation and arytenoid adduction, and further improving to 0.4 at 3 months postoperative, which was a not statistically significant improvement (p = 0.2). The intraoperative subjective numeric rating scale showed a statistically significant improvement from 3.9 preoperatively, to 6.1 after medialisation, 7.1 after medialisation and arytenoid adduction and a 7.6 at 3 months postoperative (p = 0.001). The Voice Handicap Index total score showed a statistically significant improvement from 71 points before surgery to 13 at 3 months after surgery (p = 0.008).

conclusionsOur study using intraoperative voice measurements indicate that the addition of arytenoid adduction to medialisation thyroplasty is a benefit in selected patients although more studies are needed due to the many limitations inherent to this field of investigation.

Indexed as

LaryngoplastyVocal Cord ParalysisVoiceArytenoid CartilageHumansProspective StudiesTreatment OutcomeVoice QualityArytenoid adductionMedialisation thyroplastyVHIVocal fold paralysisVoice outcome

Identifiers

PMID38365991
PMCPMC11023975
OpenAlexW4392782775

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.