Evidence map›Paper›PMID 38365985›Full record

ArticleSleep & breathing = Schlaf & Atmung2024

A pilot study to assess the effects of preventing fluid retention in the legs by wearing compression stockings on overnight airway narrowing in mild asthma.

Xiaoshu Cao, Cristina O Francisco, Swati A Bhatawadekar, Joseph Makanjuola, Susan M Tarlo, Matthew B Stanbrook, Mark D Inman, Azadeh Yadollahi

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Xiaoshu CaoInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Cristina O FranciscoKITE- Toronto Rehabilitation Institute, University Health Network, Room 12-106, 550 University Ave., Toronto, ON, M5G 2A2, Canada.
Swati A BhatawadekarKITE- Toronto Rehabilitation Institute, University Health Network, Room 12-106, 550 University Ave., Toronto, ON, M5G 2A2, Canada.
Joseph MakanjuolaKITE- Toronto Rehabilitation Institute, University Health Network, Room 12-106, 550 University Ave., Toronto, ON, M5G 2A2, Canada.
Susan M TarloDepartment of Medicine, University of Toronto, Toronto, ON, Canada.
Matthew B StanbrookDepartment of Medicine, University of Toronto, Toronto, ON, Canada.
Mark D InmanFaculty of Medicine (Respirology), McMaster University, Hamilton, ON, Canada.
Azadeh YadollahiInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada. azadeh.yadollahi@uhn.ca.
Toronto Rehabilitation Institute · CAUniversity Health Network · CAUniversity of Toronto · CAMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNocturnal asthma is a sign of asthma worsening and could be partially due to more fluid drawn into the thorax during sleep by gravitational force and/or pharyngeal collapse in those with obstructive sleep apnea. Wearing compression stockings during the day reduces fluid shift from the legs to the neck overnight. However, the potential effect of wearing compression stockings to reduce fluid accumulation in the leg and to improve nocturnal small airway narrowing in patients with asthma has not been investigated. This study investigates whether reducing leg fluid volume by wearing compression stockings during the day would attenuate small airway narrowing in patients with asthma before and after sleep.

methodsWe enrolled 11 participants with asthma. All participants underwent overnight polysomnography with or without wearing compression stockings for 2 weeks. Before and after sleep, leg fluid volume (LFV) was measured by bioelectrical impedance, and airway narrowing was primarily assessed by respiratory system resistance and reactance at 5 Hz (R5 and X5 respectively) using oscillometry.

resultsAfter 2 weeks of wearing compression stockings, the LFV measured in the evening was reduced (∆ =  - 192.6 ± 248.3 ml, p = 0.02), and R5 and X5 improved (∆ =  - 0.7 ± 0.9 cmH

conclusionsPreventing fluid retention in the legs by wearing compression stockings for 2 weeks during the day, reduced LFV and airway narrowing in the evening in all participants with asthma, but not in the morning after sleep.

Indexed as

AsthmaPolysomnographyStockings, CompressionAdultAirway ObstructionAirway ResistanceFemaleFluid ShiftsHumansLegMaleMiddle AgedPilot ProjectsSleep Apnea, ObstructiveAirway narrowingCompression stockingsLeg fluid volumeNocturnal asthma

Identifiers

PMID38365985
OpenAlexW4391914114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.