Evidence map›Paper›PMID 38365820›Full record

ArticleImplementation science communications2024

Multilevel approaches to address disparities in lung cancer screening: a study protocol.

Randi M Williams, Julia Whealan, Kathryn L Taylor, Lucile Adams-Campbell, Kristen E Miller, Kristie Foley, George Luta, Heather Brandt, Katharine Glassmeyer, Anu Sangraula and 5 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Implementation science communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04675476 (A Multilevel Intervention to Address Health Disparities in Lung Cancer Screening), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04675476 narecruitingnot on this map

A Multilevel Intervention to Address Health Disparities in Lung Cancer Screening

TypeinterventionalSponsorGeorgetown UniversityRan2024 to 2026Enrolled368ConditionsLung CancerArmsProvider Prompt & Patient Outreach and Education
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Randi M WilliamsLombardi Comprehensive Cancer Center, Cancer Prevention and Control Program, Georgetown University Medical Center, Washington, DC, USA. rmw27@georgetown.edu.ORCID http://orcid.org/0000-0003-0837-9281
Julia WhealanLombardi Comprehensive Cancer Center, Cancer Prevention and Control Program, Georgetown University Medical Center, Washington, DC, USA.
Kathryn L TaylorLombardi Comprehensive Cancer Center, Cancer Prevention and Control Program, Georgetown University Medical Center, Washington, DC, USA.
Lucile Adams-CampbellLombardi Comprehensive Cancer Center, Cancer Prevention and Control Program, Georgetown University Medical Center, Washington, DC, USA.
Kristen E MillerMedStar Health Research Institute, Washington, DC, USA.
Kristie FoleyWake Forest University School of Medicine, Winston-Salem, NC, USA.
George LutaDepartment of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, Washington, DC, USA.
Heather BrandtEpidemiology and Cancer Control Department, St. Jude Children's Research Hospital, Memphis, TN, USA.
Katharine GlassmeyerLombardi Comprehensive Cancer Center, Cancer Prevention and Control Program, Georgetown University Medical Center, Washington, DC, USA.
Anu SangraulaLombardi Comprehensive Cancer Center, Cancer Prevention and Control Program, Georgetown University Medical Center, Washington, DC, USA.
Peyton YeeLombardi Comprehensive Cancer Center, Cancer Prevention and Control Program, Georgetown University Medical Center, Washington, DC, USA.
Kaylin CamidgeLombardi Comprehensive Cancer Center, Cancer Prevention and Control Program, Georgetown University Medical Center, Washington, DC, USA.
Joseph BlumenthalMedStar Health Research Institute, Washington, DC, USA.
Saumil ModiMedStar Health, Columbia, MD, USA.
Heather KratzThe Catholic University of America, Washington, DC, USA.
Georgetown University · USMedStar Health · USSt. Jude Children's Research Hospital · USUniversity of America · USWake Forest University · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI STEPHEN W BYERS · 1990 to 2026
$71.5M
A Multilevel intervention to address health disparities in lung cancer screeningR00CA256515 · NCI · GEORGETOWN UNIVERSITY · PI WILLIAMS, RANDI M. · 2023 to 2025
$741k
Division of Cancer Prevention, National Cancer Institute R00CA256515NCI NIH HHS P30 CA051008NCI NIH HHS R00 CA256515
6 · The paper itself

Abstract

backgroundLow-dose computed tomography (lung cancer screening) can reduce lung cancer-specific mortality by 20-24%. Based on this evidence, the United States Preventive Services Task Force recommends annual lung cancer screening for asymptomatic high-risk individuals. Despite this recommendation, utilization is low (3-20%). Lung cancer screening may be particularly beneficial for African American patients because they are more likely to have advanced disease, lower survival, and lower screening rates compared to White individuals. Evidence points to multilevel approaches that simultaneously address multiple determinants to increase screening rates and decrease lung cancer burden in minoritized populations. This study will test the effects of provider- and patient-level strategies for promoting equitable lung cancer screening utilization.

methodsGuided by the Health Disparities Research Framework and the Practical, Robust Implementation and Sustainability Model, we will conduct a quasi-experimental study with four primary care clinics within a large health system (MedStar Health). Individuals eligible for lung cancer screening, defined as 50-80 years old, ≥ 20 pack-years, currently smoking, or quit < 15 years, no history of lung cancer, who have an appointment scheduled with their provider, and who are non-adherent to screening will be identified via the EHR, contacted, and enrolled (N = 184 for implementation clinics, N = 184 for comparison clinics; total N = 368). Provider participants will include those practicing at the partner clinics (N = 26). To increase provider-prompted discussions about lung screening, an electronic health record (EHR) clinician reminder will be sent to providers prior to scheduled visits with the screening-eligible participants. To increase patient-level knowledge and patient activation about screening, an inreach specialist will conduct a pre-visit phone-based educational session with participants. Patient participants will be assessed at baseline and 1-week post-visit to measure provider-patient discussion, screening intentions, and knowledge. Screening referrals and screening completion rates will be assessed via the EHR at 6 months. We will use mixed methods and multilevel assessments of patients and providers to evaluate the implementation outcomes (adoption, feasibility, acceptability, and fidelity). DISCUSSION: The study will inform future work designed to measure the independent and overlapping contributions of the multilevel implementation strategies to advance equity in lung screening rates.

trial registrationClinicalTrials.gov, NCT04675476. Registered December 19, 2020.

Indexed as

Disparities in lung cancer screeningLung cancer screeningMultilevel trialsPrimary care

Identifiers

PMID38365820
PMCPMC10870584
OpenAlexW4391883981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.