Evidence map›Paper›PMID 38365680›Full record

ArticleBMC complementary medicine and therapies2024

Development of propolis, hyaluronic acid, and vitamin K nano-emulsion for the treatment of second-degree burns in albino rats.

Marwan Elsamman, Ola M El-Borady, Mohanad M Nasr, Zeinab Al-Amgad, Asmaa A Metwally

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Marwan ElsammanFaculty of Biotechnology, October University for Modern Science and Arts (MSA), 6th October, Giza, Egypt.
Ola M El-BoradyInstitute of Nanoscience and Nanotechnology, Kafr Elsheikh University, Kafr Elsheikh, 33516, Egypt.
Mohanad M NasrFaculty of Biotechnology, October University for Modern Science and Arts (MSA), 6th October, Giza, Egypt.
Zeinab Al-AmgadGeneral Authority for Veterinary Services, Qena Veterinary Directorate, Qena, 83523, Egypt.
Asmaa A MetwallyDepartment of Surgery, Anesthesiology, and Radiology, Faculty of Veterinary Medicine, Aswan University, Aswan, 81528, Egypt. asmaaabdelsalam104@yahoo.com.ORCID https://orcid.org/0000-0001-8565-8220
October University of Modern Sciences and Arts · EGAswan University · EGKafrelsheikh University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burns are the fourth most common type of injury worldwide. Many patients also suffer numerous infections and complications that impair the burn healing process, which makes the treatment of burns a challenge. This study aimed to prepare and characterize nano-emulsion (NE) of propolis, hyaluronic acid, and vitamin K for treatment of second-degree burns. High-Pressure Liquid Chromatography (HPLC) was used for the qualitative assessment of the phenolic and flavonoid contents in crude propolis. The structural, optical, and morphological characterization, besides the antimicrobial, antioxidant, cytotoxicity, in-vitro, and in-vivo wound healing activities were evaluated. For in-vivo study, 30 adult male albino rats were divided randomly into control and treated groups, which were treated with normal saline (0.9%), and NE, respectively. The wounds were examined clinicopathologically on the 3rd, 7th, and 14th days. The NE revealed the formation of a mesh-like structure with a size range of 80-180 nm and a 21.6 ± 6.22 mV zeta potential. The IC

Indexed as

BurnsPropolisAnimalsAnti-Infective AgentsAntioxidantsHyaluronic AcidMaleRatsVitamin KAnti-Infective AgentsAntioxidantsHyaluronic AcidPropolisVitamin KBurnsHyaluronic acidNano-emulsionPropolisVitamin KWound healing assay

Identifiers

PMID38365680
PMCPMC10870492
OpenAlexW4391879791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.