Evidence map›Paper›PMID 38365634›Full record

ArticleBMC psychiatry2024

The effect of transcranial direct current stimulation (tDCS) on cognitive function recovery in patients with depression following electroconvulsive therapy (ECT): protocol for a randomized controlled trial.

Renqin Hu, Junyao Li, Yulin Lu, Huirong Luo, Yinlin Zhang, Xueqian Wang, Zheng Zhang, Qinghua Luo

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Renqin HuDepartment of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Junyao LiDepartment of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Yulin LuDepartment of Psychiatry, People's Hospital of Chongqing Banan District, Chongqing, China.
Huirong LuoDepartment of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Yinlin ZhangDepartment of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Xueqian WangDepartment of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Zheng ZhangDepartment of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Qinghua LuoDepartment of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. luoqinghua@hospital.cqmu.edu.cn.
Chongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CNFirst People's Hospital of Chongqing · CN

Funding

This study was supported by the Program for Youth Innovation in Future Medicine, Chongqing Medical University W0107
6 · The paper itself

Abstract

backgroundElectroconvulsive therapy (ECT) is a highly effective treatment for depressive disorder. However, the use of ECT is limited by its cognitive side effects (CSEs), and no specific intervention has been developed to address this problem. As transcranial direct current stimulation (tDCS) is a safe and useful tool for improving cognitive function, the main objective of this study was to explore the ability to use tDCS after ECT to ameliorate the cognitive side effects.

methods60 eligible participants will be recruited within two days after completing ECT course and randomly assigned to receive either active or sham stimulation in a blinded, parallel-design trial and continue their usual pharmacotherapy. The tDCS protocol consists of 30-min sessions at 2 mA, 5 times per week for 2 consecutive weeks, applied through 15-cm DISCUSSION: We describe a novel clinical trial to explore whether the administration of tDCS after completing ECT course can accelerates recovery from the CSEs. We hypothesized that the active group would recover faster from the CSEs and be superior to the sham group. If our hypothesis is supported, the use of tDCS could benefit eligible patients who are reluctant to receive ECT and reduce the risk of self-inflicted or suicide due to delays in treatment. TRIAL REGISTRATION DETAILS: The trial protocol is registered with https://www.chictr.org.cn/ under protocol registration number ChiCTR2300071147 (date of registration: 05.06.2023). Recruitment will start in November 2023.

Indexed as

Electroconvulsive TherapyTranscranial Direct Current StimulationCognitionDepressionDouble-Blind MethodHumansPrefrontal CortexRandomized Controlled Trials as TopicCambridge Neuropsychological Test Automated Battery (CANTAB)Cognitive side effectsDepressive DisorderDorsolateral prefrontal cortex (DLPFC)Electroconvulsive therapy (ECT)Transcranial direct current stimulation (tDCS)

Identifiers

PMID38365634
PMCPMC10870564
OpenAlexW4391879727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.