Evidence map›Paper›PMID 38365301›Full record

Observational studyBMJ open2024

Development and validation of new multimorbidity-weighted index for ICD-10-coded electronic health record and claims data: an observational study.

Melissa Y Wei, Aleda M Leis, Arseniy Vasilyev, Ashley J Kang

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Validating ICD code case definitions for condition case ascertainment in multimorbidity measurement: a retrospective chart review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Epidemiology of Respiratory Syncytial Virus in Adults and Children With Medically Attended Acute Respiratory Illness Over Three Seasons.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Melissa Y WeiDepartment of Internal Medicine, University of California Los Angeles, Los Angeles, California, USA mywei@mednet.ucla.edu.ORCID 0000-0001-5093-6040
Aleda M LeisDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Arseniy VasilyevDepartment of Internal Medicine, University of California Los Angeles, Los Angeles, California, USA.
Ashley J KangDepartment of Internal Medicine, University of California Los Angeles, Los Angeles, California, USA.

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WILLIAM H HERMAN · 2013 to 2026
$24.3M
CTSA K12 Program at the University of MichiganK12TR004374 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI L ELLINGROD, Leah Elizabeth Robinson · 2023 to 2026
$6.5M
New EHR-based multimorbidity index for diverse populations across the lifespan: development, validation, and applicationR01AG083370 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WEI, MELISSA · 2023 to 2025
$1.8M
Cumulative and Synergistic Impact of Chronic Diseases on Physical Functioning in Older Adults: Development and Validation of a Novel Measure of MultimorbidityK23AG056638 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEI, MELISSA · 2017 to 2022
$1.0M
NCATS NIH HHS K12 TR004374NIA NIH HHS K23 AG056638NIA NIH HHS R01 AG083370NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

objectiveMap multimorbidity-weighted index (MWI) conditions to International Classification of Diseases, 10th Revision (ICD-10), expand the conditions and codes to develop a new ICD-10-coded MWI (MWI-ICD10) and updated MWI-ICD9, and assess their consistency.

designPopulation-based retrospective cohort.

settingLarge medical centre between 2013 and 2017.

participantsAdults ≥18 years old with encounters in each of 4 years (2013, 2014, 2016, 2017).

main outcome measuresMWI conditions mapped to ICD-10 codes, and additional conditions and codes added to produce a new MWI-ICD10 and updated MWI-ICD9. We compared the prevalence of ICD-coded MWI conditions within the ICD-9 era (2013-2014), within the ICD-10 era (2016-2017) and across the ICD-9-ICD-10 transition in 2015 (washout period) among adults present in both sets of comparison years. We computed the prevalence and change in prevalence of conditions when using MWI-ICD10 versus MWI-ICD9.

results88 175 adults met inclusion criteria. Participants were 60.8% female, 50.5% white, with mean age 54.7±17.3 years and baseline MWI-ICD9 4.47±6.02 (range 0-64.33). Of 94 conditions, 65 had <1% difference across the ICD-9-ICD-10 transition and similar minimal changes within ICD coding eras.

conclusionsMWI-ICD10 captured the prevalence of chronic conditions nearly identically to that of the validated MWI-ICD9, along with notable but explicable changes across the ICD-10 transition. This new comprehensive person-centred index enables quantification of cumulative disease burden and physical functioning in adults as a clinically meaningful measure of multimorbidity in electronic health record and claims data.

Indexed as

International Classification of DiseasesMultimorbidityAdolescentAdultAgedChronic DiseaseElectronic Health RecordsFemaleHumansMaleMiddle AgedRetrospective StudiesChronic DiseaseElectronic Health RecordsEPIDEMIOLOGYGENERAL MEDICINE (see Internal Medicine)INTERNAL MEDICINEPatient-Centered Care

Identifiers

PMID38365301
PMCPMC10875470

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.