Evidence map›Paper›PMID 38364824›Full record

ArticleJournal of the American Chemical Society2024

Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical

William G Walls, Anna L Vagstad, Tyler Delridge, Jörn Piel, William E Broderick, Joan B Broderick

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. The radical SAM enzyme EpeE exhibits distinct site reactivity during the biosynthesis of the RiPP natural product epipeptide.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William G WallsDepartment of Chemistry & Biochemistry, Montana State University, Bozeman, Montana 59717, United States.ORCID 0000-0003-1692-3216
Anna L VagstadInstitute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Vladimir-Prelog-Weg 4, Zürich 8093, Switzerland.ORCID 0000-0001-8074-0137
Tyler DelridgeDepartment of Chemistry & Biochemistry, Montana State University, Bozeman, Montana 59717, United States.
Jörn PielInstitute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Vladimir-Prelog-Weg 4, Zürich 8093, Switzerland.
William E BroderickDepartment of Chemistry & Biochemistry, Montana State University, Bozeman, Montana 59717, United States.ORCID 0000-0001-5782-7322
Joan B BroderickDepartment of Chemistry & Biochemistry, Montana State University, Bozeman, Montana 59717, United States.ORCID 0000-0001-7057-9124

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Radical SAM Enzymes: Radical Mechanisms Central to BiologyR35GM131889 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Joan B Broderick · 2019 to 2026
$3.0M
NIGMS NIH HHS P20 GM103474NIGMS NIH HHS R35 GM131889
6 · The paper itself

Abstract

OspD is a radical

Indexed as

MethionineS-AdenosylmethionineAmino AcidsCarbonPeptidesRacemethionineValineAmino AcidsCarbonMethioninePeptidesRacemethionineS-AdenosylmethionineValine

Identifiers

PMID38364824
PMCPMC11302384

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.