Evidence map›Paper›PMID 38363767›Full record

ArticlePloS one2024

Early discharge following colectomy for colon cancer: A national perspective.

Arjun Verma, Syed Shahyan Bakhtiyar, Konmal Ghazal Ali, Nikhil Chervu, Sara Sakowitz, Hanjoo Lee, Peyman Benharash

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Arjun VermaCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America.
Syed Shahyan BakhtiyarCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America.
Konmal Ghazal AliCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America.
Nikhil ChervuCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America.ORCID 0000-0003-0327-9847
Sara SakowitzCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America.
Hanjoo LeeCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America.
Peyman BenharashCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America.ORCID 0000-0002-4705-0262
University of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough early discharge after colectomy has garnered significant interest, contemporary, large-scale analyses are lacking.

objectiveThe present study utilized a national cohort of patients undergoing colectomy to examine costs and readmissions following early discharge.

methodsAll adults undergoing elective colectomy for primary colon cancer were identified in the 2016-2019 Nationwide Readmissions Database. Patients with perioperative complications or prolonged length of stay (>8 days) were excluded to enhance cohort homogeneity. Patients discharged by postoperative day 3 were classified as Early, and others as Routine. Entropy balancing and multivariable regression were used to assess the risk-adjusted association of early discharge with costs and non-elective readmissions. Importantly, we compared 90-day stroke rates to examine whether our results were influenced by preferential early discharge of healthier patients.

resultsOf an estimated 153,996 patients, 45.5% comprised the Early cohort. Compared to Routine, the Early cohort was younger and more commonly male. Patients in the Early group more commonly underwent left-sided colectomy and laparoscopic operations. Following multivariable adjustment, expedited discharge was associated with a $4,500 reduction in costs as well as lower 30-day (adjusted odds ratio [AOR] 0.74, p<0.001) and 90-day non-elective readmissions (AOR 0.74, p<0.001). However, among those readmitted within 90 days, Early patients were more commonly readmitted for gastrointestinal conditions (45.8 vs 36.4%, p<0.001). Importantly, both cohorts had comparable 90-day stroke rates (2.2 vs 2.1%, p = 0.80).

conclusionsThe present work represents the largest analysis of early discharge following colectomy for cancer and supports its relative safety and cost-effectiveness.

Indexed as

ColectomyColonic NeoplasmsPatient DischargeAdultFemaleHumansLength of StayMalePatient ReadmissionPostoperative ComplicationsStrokeTime Factors

Identifiers

PMID38363767
PMCPMC10871523
OpenAlexW4391885613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.